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A 14-year-old, male castrated, Domestic Short Hair cat was presented for thoracic duct ligation via thoracoscopy. To optimise surgical visualisation, the surgeons requested one-lung ventilation. Because adequately sized bronchial blockers or fibreoptic bronchoscopes were not available, a modified single-lumen endotracheal tube guided by a novel method was used. The distance between the incisors, the carina and the mainstem bronchi was premeasured on a computed tomography scan. Once under general anaesthesia, one-lung ventilation was achieved by introducing a guidewire through a modified, previously extended endotracheal tube, confirming its advancement towards the left main bronchus with fluoroscopy, and subsequently advancing the endotracheal tube over the guidewire. Confirmation of one-lung ventilation was initially obtained by observation of unilateral thoracic excursions and later confirmed by thoracoscopic visualisation of right lung atelectasis. The manoeuvre was successfully completed in 8 minutes and no clinically significant complications occurred. Adequate ventilation was achieved using pressure control mode and positive end-expiratory pressure, and allowing permissive hypercapnia. After thoracic duct ligation, bilateral lung ventilation was resumed by slight withdrawal of the endotracheal tube. The cat was allowed to recover from anaesthesia and transferred to the intensive care unit. This report describes a novel method to achieve one-lung ventilation in a cat that may constitute a valid alternative when adequately sized bronchial blockers or fibreoptic bronchoscopes are not available.
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http://dx.doi.org/10.1016/j.vaa.2025.01.010 | DOI Listing |
PLoS One
September 2025
Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Purpose: Uncertainty persists regarding the optimal mode of mechanical ventilation for laparoscopic perioperative periods. Electrical impedance tomography (EIT) is an effective tool for monitoring and guiding lung-protective ventilation. This study aimed to compare the effects of pressure-controlled ventilation-volume guaranteed (PCV-VG) and volume-controlled ventilation (VCV) on pulmonary ventilation during laparoscopic surgery.
View Article and Find Full Text PDFNPJ Biol Phys Mech
September 2025
Department of Biomedical Engineering, Boston University, Boston, MA USA.
The lung undergoes continuous remodeling throughout normal development and aging, including changes to alveolar and capillary structure and function. While histological methods allow for static analysis of these age-related changes, characterizing the changes that occur in response to mechanical stimuli remains difficult, particularly over a dynamic, physiologically relevant range in a functioning lung. Alveolar and capillary distension - the change in diameter of alveoli and capillaries, respectively, in response to pressure changes - is one such process, where dynamically controlling and monitoring the diameter of the same capillary or alveolus is essential to inferring its mechanical properties.
View Article and Find Full Text PDFJ Physiol
September 2025
Institue for Exercise and Environmental Medicine, Texas Presbyterian Hospital, Dallas, TX, USA.
Some patients with heart failure with preserved ejection fraction (HFpEF) have demonstrated evidence of exercise-induced arterial hypoxaemia (EIAH). However, EIAH was not quantified using , , and measurements as previously conducted in healthy adults nor was EIAH quantified alongside simultaneous measurements of pulmonary vascular pressures, cardiorespiratory responses, or dyspnoea on exertion (DOE) in these patients. Given the effects of hypoxaemia on pulmonary vasoconstriction, cardiorespiratory responses, and DOE, we tested the hypothesis that patients with HFpEF and EIAH (EIAH) would demonstrate higher pulmonary vascular pressures, worse oxygen uptake, and greater DOE compared with patients without EIAH (EIAH).
View Article and Find Full Text PDFResuscitation
September 2025
Department of Pediatrics, Division of Neonatology, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Division of Neonatology, 2(nd) Floor, Main Building, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Aim: Flow disruptions (FDs) are deviations in the progression of care that compromise safety and efficiency of a specific process. Neonatal intubation is a life-saving high-risk procedure required for delivery room (DR) management of neonates with moderate to severe congenital diaphragmatic hernia (CDH). This study evaluated FDs during DR intubation of neonates with CDH and their association with process and outcome measures.
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