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Nasal augmentation using dermal fillers has become a popular nonsurgical esthetic procedure, particularly among Asian populations. This review explores the anatomical considerations, injection techniques, and safety measures essential for successful outcomes. The complex nasal anatomy, comprising 5 distinct soft tissue layers and intricate vascular networks, necessitates a thorough understanding to minimize risks of complications such as skin necrosis and visual impairment. The authors discuss the ideal nasal proportions and angles, emphasizing the importance of tailoring treatments to individual ethnic characteristics. The article outlines both needle-based and cannula-based injection techniques for the nasal dorsum, tip, and columella, highlighting the advantages and precautions for each approach. The dual-plane remodeling technique, utilizing firm and soft fillers, is presented as an advanced method for comprehensive nasal reshaping. Special attention is given to the columella injection technique, which addresses both esthetic and functional aspects of nasal tip projection. The discussion emphasizes the importance of choosing appropriate fillers, understanding vascular anatomy, and employing safe injection practices. As the field of non-surgical rhinoplasty evolves, continued refinement of techniques and ongoing research are crucial for enhancing safety and expanding the range of achievable outcomes in nasal augmentation with dermal fillers.
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http://dx.doi.org/10.1097/SCS.0000000000011110 | DOI Listing |
Curr Opin Endocrinol Diabetes Obes
October 2025
Department of Surgery, American Mission Hospital, Manama, Bahrain.
Purpose Of Review: To review the current medical evidence in the diagnosis and management of thyroid nodules.
Recent Findings: The widespread use of imaging modalities in recent years has led to frequent discovery of incidental thyroid nodules. These nodules are mostly benign (over 90%), hence precise insight in evaluating nodules of concern and following up other nodules is important to avoid unnecessary surgeries and its complications.
J Cosmet Dermatol
September 2025
Department of Dermatology, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China.
Purpose: To evaluate the efficacy and underlying mechanism of advanced optimal pulse technology intense pulsed light (AOPT) in low-energy triple-pulse long-width mode (AOPT-LTL) for melasma treatment.
Methods: An in vivo guinea pig model of melasma was established through progesterone injection and ultraviolet B radiation. Three sessions of AOPT-LTL treatment were performed weekly.
Korean J Anesthesiol
September 2025
Department of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15588, the Republic of Korea.
Background: Despite the well-known effects of elevated bilirubin in neonates, its neurotoxic potential in adults remains uncertain. In perioperative and hepatic disease contexts, transient bilirubin elevations are common; however, their direct contribution to cognitive dysfunction has not been clearly established. This study aimed to determine whether transient bilirubin elevation alone can impair cognition and disrupt blood-brain barrier (BBB) function in adult zebrafish, and to compare these effects with those of liver injury.
View Article and Find Full Text PDFMed Sci Monit Basic Res
August 2025
First Clinical Medical College, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
BACKGROUND This study aims to explore the therapeutic mechanisms of Jinshuiqing (JSQ) in IgA nephropathy (IgAN) using transcriptomic analysis and animal experimentation. MATERIAL AND METHODS Six-week-old male C57BL/6 mice (20±2 g) were divided into 2 groups: IgAN model and JSQ-treated. The IgAN model was induced in SIRT3 knockout mice with acidified BSA, CCl4, castor oil, and LPS injections.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
Clinical Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Objectives: To investigate the therapeutic mechanism of 2,6-dimethoxy-1,4-benzoquinone (DMQ) for alleviating dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice.
Methods: Eighteen male C57BL/6J mice were equally randomized into control group, DSS group and DMQ treatment group. In DSS and DMQ groups, the mice were treated with DSS in drinking water to induce UC, and received intraperitoneal injections of sterile PBS or DMQ (20 mg/kg) during modeling.