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It is tempting to ascribe the most outstanding achievements and discoveries in history to inborn talent, exclusive to only a handful of gifted individuals. Nevertheless, such feats are convincingly secondary to the potential for mastery-something we all share. Many studies demonstrate phenomena, such as perceptual learning, that corroborate a human's potential for mastery. This mutual power latently resides in the mind and needs to be turned on and exercised with patience and tenacity in order to reap its benefits. The potential for mastery when reached, not inborn talent, will enable oral and maxillofacial surgeons to innovate and move the field forward.
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http://dx.doi.org/10.1007/s12663-023-01974-9 | DOI Listing |
Orphanet J Rare Dis
March 2025
Department of Neurology, Shandong Key Laboratory of Mitochondrial Medicine and Rare Diseases, Research Institute of Neuromuscular and Neurodegenerative Diseases, Qilu Hospital of Shandong University, No. 107 West Wenhua Road, Jinan, 250012, Shandong, China.
Background: Mutations in the TK2 gene are strongly associated with mitochondrial DNA depletion syndrome (MDS), a severe condition with high mortality and poor outcomes. Although many MDS cases are reported, those linked to TK2 mutations with lipid deposition are rare. Large deletions in the TK2 gene are even rarer.
View Article and Find Full Text PDFJ Clin Immunol
February 2025
Department of Rheumatology & Immunology, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing
Deficiency in ELF4, X-linked (DEX) is a newly identified monogenic autoinflammatory disease. Most reported cases are male, leading to the recognition of DEX being primarily limited to male patients. Here we described 3 pediatric female patients with DEX from 3 unrelated families, who are all heterozygous for ELF4 mutations (c.
View Article and Find Full Text PDFZhonghua Gan Zang Bing Za Zhi
January 2025
First Department of The Liver Disease Center, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China.
J Maxillofac Oral Surg
February 2025
Department of Oral and Maxillofacial Surgery, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA USA.
It is tempting to ascribe the most outstanding achievements and discoveries in history to inborn talent, exclusive to only a handful of gifted individuals. Nevertheless, such feats are convincingly secondary to the potential for mastery-something we all share. Many studies demonstrate phenomena, such as perceptual learning, that corroborate a human's potential for mastery.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
November 2024
Department of Endocrinology, the Affiliated Hospital of Kunming University of Science and Technology, the First People's Hospital of Yunnan Province, Kunming650000, China.
This article reports a patient presenting with"extremely low uric acid levels in blood and urine"clinically along with reviewing relevant literature to consider a diagnosis of xanthinuria. Peripheral blood samples of the patient and her family were further collected for xanthine dehydrogenase(XDH) gene sequencing, showing that the patient had compound heterozygous mutations in exon 19:c.1995_2006del12(p.
View Article and Find Full Text PDF