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Purpose: We investigated the clinical features, current negative-pressure wound therapy (NPWT) management strategies, and outcomes of pelvic-perineal soft tissue infection after open pelvic fractures.
Materials And Methods: We analyzed the data of patients admitted to our trauma center with pelvic-perineal soft tissue after open pelvic fractures over a 7-year period. We investigated the injury severity score (ISS), medical costs, number of NPWTs, time required to reach definite wound coverage, complications, fracture classifications, transfusion requirements, interventions, length of stay (LOS) in hospital and intensive care unit (ICU), and prognosis.
Results: Twenty patients with open pelvic fractures were treated with NPWT, and one patient who underwent NPWT died of pelvic sepsis during ICU treatment. The median LOS in hospital and medical costs were 98 [56-164] days and 106400 [65600-171100] USD, respectively. Patients treated with instillation NPWT (iNPWT, n=10) had a shorter NPWT duration (24 [13-39] vs. 46 [42-91] days, =0.023), time to definite wound coverage (30 [21-43] vs. 49 [42-93] days, =0.026), and hospital LOS (56 [43-72] vs. 158 [101-192] days, =0.001), as well as lower medical costs (67800 [42500-102500] vs. 144200 [110400-236000] USD, =0.009) compared to those treated with conventional NPWT.
Conclusion: NPWT is a feasible method for treating pelvic soft tissue infections in patients with open pelvic fractures. iNPWT can reduce the duration of NPWT, hospital LOS, and medical costs.
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http://dx.doi.org/10.3349/ymj.2023.0473 | DOI Listing |
Curr Obes Rep
September 2025
Department of Medicine, Division of Endocrinology, University of Arizona, Tucson, AZ, USA.
Purpose Of The Review: This review aimed to summarize current evidence on the effectiveness of medical nutrition therapy (MNT) in the management of obesity and endometriosis, with a focus on dietary patterns such as the Mediterranean and Ketogenic diets, as well as nutritional supplementation. Additionally, it highlights the central role of the clinical nutritionist in implementing individualized, evidence-based interventions within multidisciplinary care.
Recent Findings: Although the literature reports the existence of an inverse relationship between risk of endometriosis and body mass index, clinical evidence jointly reports that a condition of obesity is associated with greater disease severity.
Cureus
August 2025
Department of Surgical Oncology, CION Cancer Clinics, Hyderabad, IND.
Extra-ovarian recurrence of mucinous cystadenomas (MCs) is a rare phenomenon. This case report presents the first documented instance of a benign MC recurring within the uterine myometrium of a 48-year-old woman. Two years following an oophorectomy for a large left ovarian MC, the patient presented with lower abdominal pain.
View Article and Find Full Text PDFCureus
August 2025
Acute Internal Medicine, University Hospitals of North Midland, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Infective endocarditis is a potentially fatal condition that can present with non-specific symptoms and rare hematologic manifestations, posing significant diagnostic challenges. We report a compelling case of a 67-year-old male with a history of type 2 diabetes, hypertension, and hyperlipidemia who sought medical attention for a five-month history of progressive iron deficiency anemia, accompanied by weight loss, fatigue, and vague constitutional symptoms. Initial extensive workup, including computed tomography of the thorax, abdomen, and pelvis, gastroscopy, colonoscopy, and transthoracic echocardiography, failed to identify an underlying cause.
View Article and Find Full Text PDFCureus
August 2025
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, USA.
Extra-pelvic endometriosis, defined as the presence of endometrial tissue or stroma outside of the pelvic cavity, is a rare cause of hemothorax and hemoperitoneum. Here, we present a case of a 34-year-old woman with a history of endometriosis who experienced recurrent, cyclical episodes of hemorrhagic pleural effusions and ascites. Despite multiple surgeries to address the ectopic endometrial implants, her symptoms persisted for years without definitive resolution, illustrating the challenges of treatment even after the diagnosis has been established.
View Article and Find Full Text PDFJ Laparoendosc Adv Surg Tech A
September 2025
Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, Florida, USA.
Robotic-assisted proctectomy (RAP) has been reportedly associated with lower rates of conversion to laparotomy than laparoscopy in several cohort studies. This st0udy aimed to assess the temporal trends in conversion from RAP to laparotomy stratified by patient and treatment-related factors. This retrospective observational study was undertaken to analyse the temporal trends in unplanned conversion from RAP to laparotomy.
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