Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The intestinal development and nutritional needs of piglets after birth are similar to those of human infants.
Objectives: This study aimed to investigate the effect of different forms of odd-chain fatty acids (OCFAs) on the growth and intestinal morphology and function of milk replacer-fed piglets, as a model for human infants.
Methods: Forty 7-d-old piglets from 8 sows were randomly assigned into 5 groups (n = 8, each from a different litter) and fed sow milk or milk replacers supplemented with different kinds of fats (control fats, docosahexaenoic acid algal oil-, OCFA algal oil-, and OCFA-enriched fats) for 21 d. One-way analysis of variance was performed to compare the milk replacer-fed piglet groups, and unpaired t test was used to compare sow milk- and milk replacer-fed piglets.
Results: Milk replacers supplemented with OCFA-enriched fats increased the average daily gain (ADG), ratio of villus height to crypt depth, and protein expression of Ki67, phosphorylated (p)-mTOR, p-S6K1, Occludin, Claudin, and ZO-1 in the selected intestines of piglets and decreased the protein expression of p-ULK1, Parkin, and PINK1 to levels similar to those of the sow milk-fed group (P < 0.05).
Conclusion: Overall, milk replacers supplemented with OCFA-enriched fats improved the ADG and the intestinal morphology and function of piglets to levels comparable to those of the sow milk-fed piglets.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.tjnut.2025.01.021 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Urinary dynamics and analytical composition of neonatal Brown Swiss calves' urine during the first week postpartum fed either dam's milk or milk replacer.
J Dairy Sci
August 2025
Professorship of Animal Nutrition and Metabolism, TUM School of Life Sciences, Technical University of Munich, Liesel-Beckmann Str. 2, 85354, Freising, Germany; HEF World Agricultural Systems Centre, Technical University of Munich, Liesel-Beckmann Str. 2, 85354, Freising, Germany. Electronic address
Monitoring urine composition is a valuable method for identifying metabolic disorders and diseases noninvasively. This study analyzed urination events, urine amounts, and urine composition in dairy calves during their first week of life, comparing calves fed dam's milk to calves fed milk replacer. Calves (n = 18) were housed individually in calf hutches and fed twice daily in unlimited amounts their dams' milk for the first 6 feedings, then switched to milk replacer or continued receiving dam's milk.
View Article and Find Full Text PDFOdd-Chain Fatty Acid-Enriched Fats Improve Growth and Intestinal Morphology and Function in Milk Replacer-Fed Piglets.
J Nutr
May 2025
Wilmar (Shanghai) Biotechnology R&D Center Co., Ltd., Shanghai, China. Electronic address:
Background: The intestinal development and nutritional needs of piglets after birth are similar to those of human infants.
Objectives: This study aimed to investigate the effect of different forms of odd-chain fatty acids (OCFAs) on the growth and intestinal morphology and function of milk replacer-fed piglets, as a model for human infants.
Methods: Forty 7-d-old piglets from 8 sows were randomly assigned into 5 groups (n = 8, each from a different litter) and fed sow milk or milk replacers supplemented with different kinds of fats (control fats, docosahexaenoic acid algal oil-, OCFA algal oil-, and OCFA-enriched fats) for 21 d.
Growth and body composition of dairy calves fed only milk replacer at 3 intakes.
J Dairy Sci
October 2024
Department of Animal Sciences, University of Illinois, Urbana, IL 61801. Electronic address:
Determination of energy requirements for growth depends on measuring the composition of BW gain. Previous studies have shown that the composition of gain can be altered in young dairy calves by the composition of the milk replacer diet. Here, our objective was to determine body composition and the composition of empty body gain in young calves fed increasing amounts of a milk replacer containing adequate CP.
View Article and Find Full Text PDFSupplementation of palmitoleic acid improved piglet growth and reduced body temperature drop upon cold exposure.
J Anim Sci
January 2023
Department of Animal and Veterinary Sciences, Aarhus University AU-Viborg, DK-8830 Tjele, Denmark.
Piglet survival is a major challenge in the first few days postpartum and interventions during this period may improve survival and growth. This study investigated the effects of palmitoleic acid (C16:1n-7; PA) supplementation on growth performance, body temperature, fatty acid (FA), and energy metabolism in milk-replacer-fed piglets. Forty-eight piglets were stratified by body weight and randomly assigned to one of four dietary treatments (0%, 1%, 2%, and 3% PA supplementation as a percent of milk replacer) and given the diet through an orogastric tube.
View Article and Find Full Text PDFEffects of supplementing milk replacer with essential amino acids on blood metabolites, immune response, and nitrogen metabolism of Holstein calves exposed to an endotoxin.
J Dairy Sci
August 2023
Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003. Electronic address:
This study evaluated the effects of supplementing calf milk replacer with essential AA on immune responses, blood metabolites, and nitrogen metabolism of 32 Holstein bull calves [28 d of age, 44 ± 0.8 kg of body weight (BW)] exposed to lipopolysaccharide (LPS). Calves were bottle-fed a commercial milk replacer (20% crude protein and 20% fat, dry matter basis) twice daily along with a calf starter (19% crude protein, dry matter basis) for 45 d.
View Article and Find Full Text PDF