Genomic insights into a diarrheal outbreak in Bangladesh reveal novel ETEC lineages and expansion of CS23 colonization factor.

Enterotoxigenic (ETEC), a leading cause of diarrhea, is defined by heat-stable (ST) and/or heat-labile (LT) toxins and associated colonization factors (CFs). However, there is still a knowledge gap in understanding ETEC's evolution, particularly in endemic regions like Bangladesh. This study investigates the genomic attributes contributing to the rise of ETEC-associated diarrhea in Bangladesh during 2022-2023.

A Cross-Sectional Study on Gastric Diseases and FGIDs in Bangladesh: Insights Into Causes, Symptoms, and Medications.

Background And Aims: Acute gastritis affects roughly 8 out of every 1000 people, while chronic gastritis affects about 2 out of every 10,000 people worldwide. When something destroys or affects the mucosa lining the stomach, which protects it from the powerful stomach acid that breaks down food, the mucosa becomes inflamed, causing gastritis. A questionnaire-based survey was designed to assess the epidemiology of gastritis based on the patient's symptomatology and potential causes of these symptoms, severity, current epidemiology, treatment, and assessment of the health-related quality of life with response to treatment and medication awareness of gastritis-related diseases in Bangladesh.

Echocardiographic assessment of pediatric lupus nephritis and its correlation with disease activity in a tertiary care hospital.

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. Lupus Nephritis (LN) is the most serious presentation. Cardiovascular complications in SLE and LN can cause significant morbidity and mortality.

Evaluation of colonization factors of ETEC isolated from diarrheal patients in Bangladesh: A comparative approach using multiplex PCR and dot blot immunoassay.

Enterotoxigenic Escherichia coli (ETEC) harbors colonization factors (CFs) to colonize the small intestine. In this study, as part of routine systematic ETEC surveillance in Bangladesh, we evaluated CFs from ETEC isolated from hospitalized diarrheal patients using a multiplex PCR assay for the first time, as the availability of the monoclonal antibodies for dot blot assay became limited. A total of 5914 diarrheal patients were enrolled during the study period (2023-2024), and a PCR assay, targeting heat-labile toxin (LT) and heat-stable toxin (ST), found 531 ETEC-infected patients.

Social Media Use Time and Mental Health of Young Adults: A Cross-Sectional Study in Bangladesh.

Background: Social media (SM) use has gained much popularity among young adults, which could impact their mental health. The association between SM use time and young adults' mental health in Bangladesh has been less researched.

Aim: To determine the association between SM use time and mental health among young adults in Bangladesh.