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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049199PMC
http://dx.doi.org/10.4103/aian.aian_726_24DOI Listing

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Article Synopsis
  • MOGAD is usually linked to inflammation and demyelination in younger people, but this case shows it can also cause isolated encephalitis in older adults, like an 80-year-old male with cognitive issues and seizures.
  • Despite normal imaging results, the patient had elevated MOG antibodies and pleocytosis in cerebrospinal fluid, pointing towards MOG antibody encephalitis.
  • Treatment with intravenous immunoglobulin led to significant cognitive improvement and a reduction in antibody levels, highlighting the need for awareness of MOGAD in elderly patients to improve outcomes.
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