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Study Objectives: Both the (ICSD) and the sleep-wake disorders section of the (DSM) emphasize the importance of clinical judgment in distinguishing the normal from the pathological in sleep medicine. The fourth edition of the DSM (DSM-IV, 1994) introduced the clinical significance criterion (CSC) to standardize this judgment and enhance diagnostic reliability.
Methods: This review conducts a theoretical and historical content analysis of CSC presence, frequency, and formulation in the diagnostic criteria of sleep disorders. Three steps were undertaken: (1) selecting main sleep disorder classifications and main disorders within them, (2) systematically extracting CSC-related content, and (3) analyzing the evolution of CSC presence through quantification (Jaccard index) and visualization (radar plots).
Results: The fifth edition, text revision of the DSM (DSM-5-TR) includes CSC in 5 of 9 main sleep disorders, compared to 2 in the third edition, text revision of the ICSD (ICSD-3-TR) (circadian rhythm sleep-wake disorder and nightmare disorder). The overlap between DSM-5-TR and ICSD-3-TR is moderate (Jaccard index = 0.40). The overlap between DSM versions is higher (0.53). Conversely, ICSD revisions exhibit minimal similarity (0.16). Radar plots reveal a gradual increase in CSC use within ICSD versions.
Conclusions: These results highlight the variable application of CSC in sleep disorder classifications. Universal CSC inclusion may not be essential, but systematic discussion of its potential use can help refine diagnostic criteria. This refinement is important for accurately diagnosing sleep disorders and better differentiating the normal from the pathological, a major challenge in sleep medicine.
Citation: Gauld C, Martin VP, Quilès C, et al. Clinical significance criteria in the ICSD and DSM sleep disorder classifications: a content overlap analysis using the Jaccard index. . 2025;21(6):1109-1121.
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http://dx.doi.org/10.5664/jcsm.11570 | DOI Listing |
BMC Pediatr
September 2025
School of Health and Welfare, Halmstad University, Halmstad, Sweden.
Background: Adequate sleep is crucial for children's health, especially for children with ADHD and concurrent sleep problems. There is a need for more studies focusing on sleep problems in children with ADHD as these problems may exacerbate ADHD symptoms and vice versa, impacting negatively on everyday life. The aim of this study was to investigate the differences in health-related factors between children with ADHD without clinically relevant sleep problems and those with clinically relevant sleep problems after a sleep intervention.
View Article and Find Full Text PDFSci Rep
September 2025
College of First Clinical Medical, Shandong University of Traditional Chinese Medicine, Jinan, China.
Obstructive sleep apnea (OSA) is associated with metabolic disorders such as insulin resistance and liver fat accumulation. However, the specific mediating role of liver-related metabolic indicators in this association has not been fully studied. The purpose of this study was to investigate the relationship between Metabolic Score for Insulin Resistance (METS-IR) and OSA, focusing on the mediating effects of liver fat percentage (PLF) and hepatic steatosis index (HSI).
View Article and Find Full Text PDFCommun Biol
September 2025
Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sleep is a complex behavior regulated by various brain cell types. However, the roles of brain-resident macrophages, including microglia and CNS-associated macrophages (CAMs), particularly those derived postnatally, in sleep regulation remain poorly understood. Here, we investigated the effects of resident (embryo-derived) and repopulated (postnatally derived) brain-resident macrophages on the regulation of vigilance states in mice.
View Article and Find Full Text PDFJ Voice
September 2025
Department of Speech-Language-Hearing Sciences, Medical School, Federal University of Minas Gerais - UFMG, Belo Horizonte, Minas Gerais, Brazil. Electronic address:
Objective: To analyze the association between the risk of voice disorders and sociodemographic, work, and general health factors in urban and rural school teachers.
Methods: This is an observational, cross-sectional, analytical study with 1705 teachers from urban schools and 202 from rural schools teaching elementary and high school in Minas Gerais, Brazil. The exclusion criteria were being retired or no longer teaching and/or not accepting to participate in the study.
Zhonghua Jie He He Hu Xi Za Zhi
September 2025
Neuromuscular diseases are often accompanied by various types of sleep-related breathing disorders, which can exacerbate the underlying condition and are associated with a poor prognosis. Early identification is essential, and interventions such as non-invasive ventilation, oxygen therapy, and respiratory rehabilitation should be initiated promptly to mitigate disease progression and improve outcomes. Nevertheless, the rates of missed and misdiagnosed cases remain common in clinical practice.
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