Multimodal artificial intelligence system for detecting a small esophageal high-grade squamous intraepithelial neoplasia: A case report.

World J Gastrointest Endosc

Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Published: January 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Recent advancements in artificial intelligence (AI) have significantly enhanced the capabilities of endoscopic-assisted diagnosis for gastrointestinal diseases. AI has shown great promise in clinical practice, particularly for diagnostic support, offering real-time insights into complex conditions such as esophageal squamous cell carcinoma.

Case Summary: In this study, we introduce a multimodal AI system that successfully identified and delineated a small and flat carcinoma during esophagogastroduodenoscopy, highlighting its potential for early detection of malignancies. The lesion was confirmed as high-grade squamous intraepithelial neoplasia, with pathology results supporting the AI system's accuracy. The multimodal AI system offers an integrated solution that provides real-time, accurate diagnostic information directly within the endoscopic device interface, allowing for single-monitor use without disrupting endoscopist's workflow.

Conclusion: This work underscores the transformative potential of AI to enhance endoscopic diagnosis by enabling earlier, more accurate interventions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752473PMC
http://dx.doi.org/10.4253/wjge.v17.i1.101233DOI Listing

Publication Analysis

Top Keywords

artificial intelligence
8
high-grade squamous
8
squamous intraepithelial
8
intraepithelial neoplasia
8
multimodal system
8
multimodal artificial
4
intelligence system
4
system detecting
4
detecting small
4
small esophageal
4

Similar Publications

Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that regulate gene expression in response to metabolic, hormonal, and environmental signals. These receptors play a critical role in metabolic homeostasis, inflammation, immune function, and disease pathogenesis, positioning them as key therapeutic targets. This review explores the mechanistic roles of NRs such as PPARs, FXR, LXR, and thyroid hormone receptors (THRs) in regulating lipid and glucose metabolism, energy expenditure, cardiovascular health, and neurodegeneration.

View Article and Find Full Text PDF

Aim: The purpose of this study was to assess the accuracy of a customized deep learning model based on CNN and U-Net for detecting and segmenting the second mesiobuccal canal (MB2) of maxillary first molar teeth on cone beam computed tomography (CBCT) scans.

Methodology: CBCT scans of 37 patients were imported into 3D slicer software to crop and segment the canals of the mesiobuccal (MB) root of the maxillary first molar. The annotated data were divided into two groups: 80% for training and validation and 20% for testing.

View Article and Find Full Text PDF

Obsessive-compulsive disorder (OCD) is a chronic and disabling condition affecting approximately 3.5% of the global population, with diagnosis on average delayed by 7.1 years or often confounded with other psychiatric disorders.

View Article and Find Full Text PDF

Use of artificial intelligence for classification of fractures around the elbow in adults according to the 2018 AO/OTA classification system.

BMC Musculoskelet Disord

September 2025

Department of Clinical Sciences at Danderyds Hospital, Department of Orthopedic Surgery, Karolinska Institutet, Stockholm, 182 88, Sweden.

Background: This study evaluates the accuracy of an Artificial Intelligence (AI) system, specifically a convolutional neural network (CNN), in classifying elbow fractures using the detailed 2018 AO/OTA fracture classification system.

Methods: A retrospective analysis of 5,367 radiograph exams visualizing the elbow from adult patients (2002-2016) was conducted using a deep neural network. Radiographs were manually categorized according to the 2018 AO/OTA system by orthopedic surgeons.

View Article and Find Full Text PDF

Purpose: The study aims to compare the treatment recommendations generated by four leading large language models (LLMs) with those from 21 sarcoma centers' multidisciplinary tumor boards (MTBs) of the sarcoma ring trial in managing complex soft tissue sarcoma (STS) cases.

Methods: We simulated STS-MTBs using four LLMs-Llama 3.2-vison: 90b, Claude 3.

View Article and Find Full Text PDF