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Article Abstract
We describe the identification of a previously unrecognized ubiquitin ligase-substrate (FBXO45-GEF-H1) regulatory axis that plays an important role in germinal center formation and pathogenesis of common BCLs. These studies reveal novel insights linking dysregulated ubiquitin-mediated control to exploitable vulnerabilities and novel therapeutic strategies for these cancers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962402 | PMC |
| http://dx.doi.org/10.1158/2159-8290.CD-24-0442 | DOI Listing |
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