98%
921
2 minutes
20
Nitrite is an important chemical intermediate in the nitrogen cycle and is ubiquitously present in environmental and biological systems as a metabolite or additive in the agricultural and food industries. However, nitrite can also be toxic in excessive concentrations. As such, the development of quick, sensitive, and portable assays for its measurement is desirable. In this review, we summarize the working principles and applications of surface-enhanced Raman spectroscopy (SERS) as a rapid, portable, and ultrasensitive method for nitrite detection and showcase its applicability in various water, food, and biological samples. The challenges and opportunities for future developments are also discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1021/acs.jafc.4c09391 | DOI Listing |
Anal Sci
September 2025
Department of Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, 739-8526, Japan.
Surface-enhanced Raman scattering (SERS) is a powerful analytical technique; however, its quantitative application has been limited by the instability of substrates and significant signal fluctuations. In this study, we demonstrated that 4-aminobenzenethiol (4-ATP) can be quantitatively detected through statistical analysis of SERS signal intensity distributions obtained using citrate-stabilized AuNPs, biotin-functionalized AuNPs, and gold nanoparticle (AuNP)-bound polystyrene (PS) microparticles. Raman spectra obtained in bulk aqueous solution under static conditions showed that the detection sensitivity of 4-ATP using AuNP-bound PS microparticles was approximately twice that achieved with citrate-stabilized AuNPs or biotin-modified AuNPs.
View Article and Find Full Text PDFAdv Mater
September 2025
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico, Universitat de València-Universitat Politècnica de València, Camino de Vera s/n, Valencia, 46022, Spain.
Bioorthogonal chemistry that can be controlled through near-infrared (NIR) light is a promising route to therapeutics. This study proposes a method to intracellularly photoactivate prodrugs using plasmonic gold nanostars (AuNSt) and NIR irradiation. Two strategies are followed.
View Article and Find Full Text PDFMikrochim Acta
September 2025
Teaching & Research Department of Common Course, Shenyang Sport University, Shenyang, 110115, China.
A surface enhanced Raman scattering (SERS)-based sensing platform is devised integrating a TMB redox system for rapid dopamine detection. Gold nanobipyramids (Au NBPs), synthesized via the heat-mediated seed-mediated growth method, possess dual functionality of peroxidase-like activity and SERS activity. This enables them to catalyze the oxidation of TMB and simultaneously amplify the Raman signal of the oxidized TMB product (oxTMB).
View Article and Find Full Text PDFTalanta
September 2025
Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Viet Nam. Electronic address:
Food spoilage poses a global challenge with far-reaching consequences for public health, economic stability, and environmental sustainability. Conventional analytical methods for spoilage detection though accurate are often cost-prohibitive, labor-intensive, and unsuitable for real-time or field-based monitoring. Microfluidic paper-based analytical devices (μPADs) have emerged as a transformative technology offering rapid, portable, and cost-effective solutions for food quality assessment.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
National Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai 200240, China.
Integrating surface-enhanced fluorescence (SEF) and surface-enhanced Raman spectroscopy (SERS) into a single probe is a natural step forward for plasmon-enhanced spectroscopy (PES), as SEF enables enhanced fluorescent imaging for fast screening of targets, while SERS allows ultrasensitive trace molecular characterization with specificity. However, many challenges remain, e.g.
View Article and Find Full Text PDF