Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1111/ijd.17637DOI Listing

Publication Analysis

Top Keywords

pathogenesis paradoxical
4
paradoxical alopecia
4
alopecia areata
4
areata dupilumab
4
dupilumab therapy
4
therapy unknown
4
pathogenesis
1
alopecia
1
areata
1
dupilumab
1

Similar Publications

Objectives: To explore the relationships between cardiac parameters and body composition indices, identifying predictors of subclinical cardiac systolic dysfunction.

Methods: Using anthropometric and serological parameters, echocardiography, and body composition analysis, this study evaluated metabolic profiles, cardiac remodeling patterns, and body composition characteristics in young adult obese patients, while quantifying the correlations between cardiac parameters and body composition indices. Subclinical left ventricular systolic dysfunction was defined as global longitudinal strain (GLS) < 18%.

View Article and Find Full Text PDF

Outcomes of overweight and obese critically ill patients with severe acute respiratory infection.

J Int Med Res

September 2025

Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Saudi Arabia.

ObjectivesTo assess the association of obesity with outcomes among patients with severe acute respiratory infection.MethodsThis is a retrospective cohort study of patients with severe acute respiratory infection admitted to the intensive care units in four referral hospitals in Saudi Arabia between September 2012 and June 2018. Patients were classified into two groups: overweight-obese patients (body mass index  ≥25 kg/m) and normal-weight patients (body mass index between 18.

View Article and Find Full Text PDF

Ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation, has emerged as a critical pathophysiological mechanism linking cancer and inflammatory diseases. The seemingly distinct pathologies exhibit shared microenvironmental hallmarks-oxidative stress, immune dysregulation, and metabolic reprogramming-that converge on ferroptosis regulation. This review synthesizes how ferroptosis operates at the intersection of these diseases, acting as both a tumor-suppressive mechanism and a driver of inflammatory tissue damage.

View Article and Find Full Text PDF

Background: Obesity is a chronic condition linked to health issues such as diabetes, heart disease, and increased cancer risk. High body mass index (BMI) is associated with cancers such as breast and colorectal cancer due to hormone imbalances and inflammation from excess fat, whereas a low BMI can raise cancer risk by weakening the immune system. Maintaining a normal BMI improves cancer treatment outcomes, but in some cases, higher BMI might offer protective effects-a phenomenon known as the "obesity paradox".

View Article and Find Full Text PDF

Role of CPEBs in Learning and Memory.

J Neurochem

September 2025

Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Memory formation involves a complex interplay of molecular and cellular processes, including synaptic plasticity mechanisms such as long-term potentiation (LTP) and long-term depression (LTD). These processes rely on activity-dependent gene expression and local protein synthesis at synapses. A central unresolved question in neuroscience is how memories can be stably maintained over time, despite the transient nature of the proteins involved in their initial encoding.

View Article and Find Full Text PDF