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What Is Already Known About This Topic?: Foodborne botulism is caused by botulinum neurotoxin (BoNT). () is a strictly anaerobic, Gram-positive bacterium, which is a key pathogen capable of producing BoNT. BoNTs can be classified into seven serotypes (A to G) based on their antigenic properties. Among these, BoNT/A is one of the most common serotypes.
What Is Added By This Report?: This was a case of foodborne botulism in Weihai caused by homemade pickled eggs contaminated with . Five individuals presented with symptoms, while three were asymptomatic. All patients received botulinum antitoxin treatment, and no deaths occurred. During this outbreak, 12 isolates of were obtained. The phylogenetic analysis results revealed that all the isolates came from the same origin.
What Are The Implications For Public Health Practice?: This outbreak indicated that foodborne botulism remains a public health issue in China. We need to strengthen publicity and education efforts to inform people of the potential risk of botulism associated with consuming homemade traditional pickled foods. Heating and boiling homemade foods thoroughly can destroy toxins and prevent foodborne botulism.
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http://dx.doi.org/10.46234/ccdcw2024.273 | DOI Listing |
BMC Neurol
August 2025
Department of Neurology, University of California, San Francisco, USA.
Background: Adult botulism is a rare, life-threatening condition typically caused by exposure to preformed botulinum neurotoxin (BoNT). Acute intestinal toxemia botulism (AITB) is an uncommon subtype resulting from colonization of Clostridium botulinum in the intestines. Diagnosis is made by detecting BoNT in the patient's blood, stool, or gastric fluid.
View Article and Find Full Text PDFCutan Ocul Toxicol
August 2025
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Study Purpose: Botulinum toxin (BoNT) is commonly used for both cosmetic and medical purposes. However, improper use can lead to iatrogenic botulism. This scoping review aimed to evaluate the systemic and skin-related effects, identify risk factors, and highlight safety gaps in BoNT-related botulism.
View Article and Find Full Text PDFACS Omega
August 2025
Human Foods Program, U.S. Food and Drug Administration, Bedford Park, Illinois 60501, United States.
Botulinum neurotoxin (BoNT) poses a significant threat to public health as the most potent toxin known to humans. BoNT intoxication can lead to botulism, a life-threatening disease that may result from ingesting food contaminated with biologically active BoNT. The gold standard method for BoNT detection, the mouse bioassay, is time-consuming and raises ethical concerns regarding the use of laboratory animals.
View Article and Find Full Text PDFFoods
July 2025
Gastrointestinal Infections, Food Safety and One Health, UK Health Security Agency, London NW9 5EQ, UK.
Food-borne botulism is a rare but serious disease caused by ingestion of botulinum neurotoxin pre-formed in food by Between 2006 and 2009, no foodborne botulism cases were reported in the UK. However, the period from 2010 to 2024 saw 13 cases, encompassing seven separate incidents and two outbreaks, with no reported fatalities. Cases were predominantly linked to imported, home-made, and artisanal foods, occasionally to commercial products.
View Article and Find Full Text PDFMicrob Genom
August 2025
Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK.
Bacteria from the species encompass a diverse range of phenotypes. While some strains are used as probiotics, others have been isolated from cases of botulism and necrotizing enterocolitis (NEC) in preterm neonates. We identify a unique genomic feature of this species, namely a highly conserved extrachromosomal element of ~0.
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