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Article Abstract
An efficient Rh(III)-catalyzed C-H activation of azobenzenes and subsequent [4+1] cascade annulation with CF-imidoyl sulfoxonium ylides was developed, yielding diverse CF-indazoles. This protocol featured easily available starting materials, excellent functional group tolerance and high efficiency. Moreover, the antitumor activities of selected CF-indazoles against human cancer cell lines were also studied, and the results indicated that several compounds displayed considerable antiproliferative activities.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11720978 | PMC |
| http://dx.doi.org/10.3390/molecules30010183 | DOI Listing |
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