Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: To analyze the prevalence and influencing factors of stroke in patients with nonvalvular atrial fibrillation (SIPWNVAF), and to provide a reference basis for the prevention and control of stroke.
Methods: Data were obtained from the China National Stroke Screening Survey. From January 2016 to December 2023, a total of 15,471 permanent residents aged ≥40 years in Yinchuan were screened. Patients with nonvalvular atrial fibrillation who had their first stroke were selected as the stroke group (86 patients), and patients with nonvalvular atrial fibrillation who had never had a stroke as the control group (477 patients).
Results: In 563 residents, the crude prevalence of SIPWNVAF was 15.28%, and the standardized prevalence was 9.33%. The multivariable logistic regression analysis revealed that age (odds ratio [OR]: 1.42; 95% confidence interval [CI]: 1.17-1.71), smoking (OR: 2.10; 95% CI: 1.46-3.01), drinking (OR: 2.00; 95% CI: 1.28-3.13), lack of exercise (OR: 2.18; 95% CI: 1.18-4.03), family history of stroke (OR: 4.39; 95% CI: 1.82-10.57), hypertension (OR: 1.94; 95% CI: 1.03-3.63), diabetes (OR: 3.10; 95% CI: 1.37-7.05), dyslipidemia (OR: 2.15; 95% CI: 1.16-3.99), homocysteine ≥15 μmol/L (OR: 2.13; 95% CI: 1.14-3.97), and carotid atherosclerosis (OR: 2.86; 95% CI: 1.53-5.37) were independent risk factors, but educational level (OR: 0.31; 95% CI: 0.17-0.58) was a protective factor for SIPWNVAF.
Conclusions: The stroke group is significantly more burdened by other independent common risk factors for stroke.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.wneu.2024.123652 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of Bleeding and Thrombotic Outcomes of Anticoagulation Strategies Upon Intensive Care Unit Admission for Patients with Atrial Fibrillation on Direct Oral Anticoagulants.
J Pharm Pract
September 2025
Department of Pharmacy, Houston Methodist Hospital, TX, USA.
Critically ill adults are more commonly being admitted to intensive care units (ICU) with a recent history of direct oral anticoagulant (DOAC) use. No consensus guidance exists on optimal anticoagulation strategies in critically ill adults with non-valvular atrial fibrillation (NVAF) on DOAC's prior to ICU admission, and there is considerable variability in clinical practice. To evaluate rates of major bleeding and thrombosis between 2 anticoagulation strategies for NVAF upon ICU admission: package insert (continuation of oral or parenteral anticoagulation per manufacturer recommendations) vs non-package insert (prophylactic dosing or delayed therapeutic anticoagulation).
View Article and Find Full Text PDFImpact of drug utilization management strategies on the incidence and cost of clinical events in patients with non-valvular atrial fibrillation receiving DOACs in the US.
J Med Econ
September 2025
Health Economics and Outcomes Research Ltd., Cardiff, United Kingdom.
Background: Medicare plans employ drug utilization management strategies, including prior authorization (PA) and step therapy (ST), or formulary tier increases, to control spending. However, PA and ST can delay treatment access and encourage use of less effective/safe therapies, while formulary tier increases can lead to treatment switching/discontinuation due to higher patient out-of-pocket costs. This study modeled the impact of restricted access to direct oral anticoagulants (DOACs), and a tier increase for apixaban, on incidence and cost of clinical events in patients with non-valvular atrial fibrillation (NVAF) in the United States.
View Article and Find Full Text PDFInteratrial block predicts left atrial appendage thrombus in nonvalvular atrial fibrillation.
J Electrocardiol
September 2025
Department of Cardiology, Ankara City Hospital, Health Sciences University, Ankara, Turkey.
Background: Interatrial block (IAB) is an electrocardiographic manifestation of atrial conduction delay and structural remodeling. While it has been linked to atrial fibrillation (AF) and thromboembolic events, its potential role in predicting left atrial appendage (LAA) thrombus formation remains underexplored. This study aimed to investigate the association between IAB and the presence of LAA thrombus in patients with nonvalvular AF (NVAF) or atrial flutter referred for rhythm control procedures.
View Article and Find Full Text PDFLeft Atrial Appendage Occlusion Devices Focused on Complications of Therapy.
Cardiol Rev
September 2025
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Left atrial appendage occlusion (LAAO) is an alternative to oral anticoagulation for stroke prevention in atrial fibrillation (AF), especially in patients at high bleeding risk. While generally safe, LAAO involves procedural and postprocedural risks. The most serious complication is pericardial effusion or tamponade; other periprocedural risks include stroke, device embolization, vascular injury, major bleeding, and air embolism.
View Article and Find Full Text PDFLeft atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing.
Neurologia (Engl Ed)
September 2025
Hospital Universitario de Salamanca, CIBERCV, IBSAL, Spain.
Background: Oral anticoagulation (OAC) use increases the risk of intracranial hemorrhage (ICH) in patients with atrial fibrillation (AF) and CHADS-VASc ≥2. Left atrial appendage occlusion (LAAO) is an alternative to OAC, however data about its use in patients with prior ICH is scarce and the timing of its performance is controversial. Furthermore, the long-term outcomes in this group of patients have not been described previously.
View Article and Find Full Text PDF