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http://dx.doi.org/10.1021/acs.est.4c13968 | DOI Listing |
Purpose: This study aims to validate the usefulness of T10-pelvic angle (T10PA) in predicting pelvic tilt (PT) restoration, proximal junctional kyphosis (PJK) development, and clinical outcomes after adult spinal deformity (ASD) surgery.
Methods: This retrospective study included 213 ASD patients who underwent fusion from the lower thoracic spine (T9 or T10) to the pelvis. T10PA was measured on 6-week postoperative radiographs as the angle between the center of T10 and the hip center, and from the hip center to the midpoint of the S1 upper endplate.
Am J Ophthalmol
September 2025
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address:
Purpose: To report on the real-world experience of using intravitreal pegcetacoplan for the treatment of geographic atrophy (GA) in age-related macular degeneration (AMD).
Design: Retrospective interventional case series.
Methods: Eyes with symptomatic GA secondary to AMD were treated with 15mg of intravitreal pegcetacoplan and participated in an ongoing prospective swept-source optical coherence tomography angiography (SS-OCTA) imaging study.
Hum Reprod Update
September 2025
Women's Health Research Collaborative, New York, NY, USA.
Background: Reproductive-age women with intrauterine adhesions (IUAs) following uterine surgery may be asymptomatic or may experience light or absent menstruation, infertility, preterm delivery, and/or peripartum hemorrhage. Understanding procedure- and technique-specific risks and the available evidence on the impact of surgical adjuvants is essential to the design of future research.
Objective And Rationale: While many systematic reviews have been published, most deal with singular aspects of the problem.
Public Health Rep
September 2025
Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Objective: Rare diseases collectively affect approximately 30 million people in the United States. Despite advances in genomic medicine, early diagnosis is challenging because of limited awareness of, accessibility to, and disparities in health care resources. We assessed the real-world experiences of patients with rare diseases in Pennsylvania and evaluated the effect of delayed diagnosis on psychosocial and financial burdens.
View Article and Find Full Text PDFUrol J
September 2025
Gazi University, Faculty of Medicine, Department of Pediatric Surgery, Ankara, Turkey.
Purpose: To review the current literature on dorsal penile curvature (DPC) in children, including its etiology, diagnosis, and principles of treatment.
Materials And Methods: A literature review was conducted on DPC in children, focusing on its etiology (e.g.