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http://dx.doi.org/10.1186/s13058-024-01952-0 | DOI Listing |
Breast Cancer Res
January 2025
Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
Zhonghua Zhong Liu Za Zhi
April 2023
Department of Life Science, Bengbu Medical College, Bengbu 233017, China.
To produce chimeric antigen receptor T cells (CAR-T) targeting human hepatocyte growth factor/c-Met (HGF/c-Met) protein and detect its cytotoxicity against non-small cell lung cancer (NSCLC) cells H1975 . The whole gene sequence of c-Met CAR containing c-Met single-chain fragment variable was synthesized and linked to lentiviral vector plasmid, plasmid electrophoresis was used to detect the correctness of target gene. HEK293 cells were transfected with plasmid and the concentrated solution of the virus particles was collected.
View Article and Find Full Text PDFBMC Cancer
August 2019
Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 in Fenglin Road, Shanghai, 200032, People's Republic of China.
Background: This study aimed to investigate the prognostic value of volumetric parameters on F- fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography/computed tomography (PET/CT) in gastric-cancer patients, according to the expression status of c-MET (MET proto-oncogene, receptor tyrosine kinase), which was previously unclear.
Methods: The study included 61 patients with advanced gastric cancer. Data on the baseline F-FDG PET/CT, clinical-pathological information, progression-free survival (PFS), and overall survival (OS) were collected.