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Importance: Health systems are increasingly required to conduct health-related social needs screening. However, how social resources negatively and positively affect recovery from acute illnesses, such as COVID-19, is incompletely understood.
Objective: To examine how social determinants of health (SDOH) influence recovery from COVID-19.
Design, Setting, And Participants: In this qualitative study, patients were recruited for semistructured interviews from a post-COVID-19 pulmonary clinic at a southeastern US academic medical center between November 2022 and March 2023. Caregivers were included in dyadic interviews when available. Interviews queried participants about SDOH domains, as defined by the US Centers for Disease Control and Prevention, and their relationship with COVID-19 recovery.
Main Outcome And Measures: Phenomenologic analysis identified themes characterizing participant perspectives on the influence of SDOH on COVID-19 recovery.
Results: A total of 24 interviews were conducted: 10 (42%) with patient-caregiver dyads, 13 (54%) with patients alone, and 1 (4%) with 2 patients who also served as each other's caregiver. Most participants were female (18 patients [72%] and 6 caregivers [60%]). The median age of patients was 57 years (IQR, 44-61 years) and of caregivers was 47 years (IQR, 39-62 years). Three cross-cutting themes that overlapped SDOH domains were identified. Participants noted that innovative mobilization of social resources (eg, policies to secure income during time away from work) supported recovery from COVID-19 illness, but destabilization and change introduced by illness (eg, disrupted social support networks) and mistrust of previously established institutions (eg, public health misinformation) hindered recovery.
Conclusions And Relevance: Participants identified 3 distinct SDOH domains positively and negatively influencing recovery from COVID-19 illness. The findings suggest that longitudinal, multidomain data on SDOH are needed to best address barriers and identify resources for patients recovering from acute illness and may help determine opportunities for system- and policy-level interventions that can mitigate the influence of long-standing structural inequities on health.
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http://dx.doi.org/10.1001/jamanetworkopen.2024.53261 | DOI Listing |
AIDS Patient Care STDS
September 2025
Department of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
Structural inequities significantly shape disparities across the HIV care continuum, yet few validated tools exist to quantify HIV-specific structural vulnerability at the population level in the United States. This study introduces and validates the HIV-Specific Social and Structural Determinants of Health Index (HIV-SSDI), a multi-dimensional, state-level index designed to capture structural disadvantage relevant to HIV prevention and care. Using publicly available state-level index (2008-2023) spanning nine structural domains, we developed the HIV-SSDI through exploratory factor analysis with three extraction methods: principal component analysis, maximum likelihood, and minimum residual.
View Article and Find Full Text PDFPediatr Neurol
August 2025
Division of Neurology, Department of Pediatrics, Nationwide Children's Hospital and the Ohio State University College of Medicine, Columbus, Ohio.
Background: Health-related quality of life (HRQoL) in children with epilepsy is a measure of the impact of epilepsy on mental and physical health. Although epilepsy features, treatments, and developmental/learning issues impact HRQoL, less data exist on how social, non-disease-related factors play a role. This retrospective observational study examines the association of social determinants of health (SDOH) with HRQoL in children with epilepsy.
View Article and Find Full Text PDFCureus
July 2025
Family Medicine and Public Health Sciences, Wayne State University School of Medicine, Detroit, USA.
Mistrust and barriers to influenza vaccination are well-documented in the literature. Underserved populations, including the Hispanic community, experience social determinants of health that exacerbate their health outcomes, including for common preventable illnesses such as influenza (flu). There is currently a gap in the literature regarding the knowledge, barriers to access, and trust of the Hispanic community regarding the influenza vaccine.
View Article and Find Full Text PDFLancet Reg Health Am
October 2025
AdventHealth Research Institute, Department of Neuroscience, AdventHealth, Orlando, FL, USA.
Background: Lower socioeconomic status (SES) is associated with increased risk of cognitive decline and dementia, yet reliance on singular indicators of SES limits understanding of these relationships. We examined multiple SES characteristics at the individual and area-levels simultaneously in association with diverse cognitive processes in a large, community-dwelling older adult sample.
Methods: Data collected at three United States sites (Boston, Pittsburgh, Kansas City) included a comprehensive cognitive assessment comprising measures of episodic memory, executive function, processing speed, working memory, and visuospatial abilities.
J Racial Ethn Health Disparities
September 2025
The Brookings Institution, 1775 Massachusetts Ave., NW, Washington, DC, 20036, USA.
Minorities' Diminished Return (MDR) theory suggests systematically smaller effects of socioeconomic status (SES) indicators on the health of non-white populations compared to white in the United States (US). We test whether MDR theory holds with regard to subjective well-being (SWB) by investigating racial differences in the association between SES and SWB in the US using data from the Gallup Healthways survey. Our analysis included 126,669 non-Hispanic Black and white US adults.
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