The Impact of Social Determinants of Health on Quality of Life in a Cohort of 1300 Children With Epilepsy.

Background: Health-related quality of life (HRQoL) in children with epilepsy is a measure of the impact of epilepsy on mental and physical health. Although epilepsy features, treatments, and developmental/learning issues impact HRQoL, less data exist on how social, non-disease-related factors play a role. This retrospective observational study examines the association of social determinants of health (SDOH) with HRQoL in children with epilepsy.

The First 100 Seconds of Sleep of rEEGs Can Be a Reliable Scoring Method for D/EE-SWAS.

Purpose: Developmental/epileptic encephalopathy with spike wave activation with sleep, formerly known as electrical status epilepticus in sleep, is an electrographic pattern in which the interictal epileptiform activity is augmented by transition to sleep. Recent studies demonstrate the utility of the first 100 seconds of sleep of long-term monitoring (LTM) as a scoring method for electrical status epilepticus in sleep. Our aim was to measure the reliability of the spike-wave index (SWI) of the first 100 seconds of sleep of routine EEG (rEEG) as a tool for diagnosis of developmental/epileptic encephalopathy with spike wave activation with sleep.

The Spike-Wave Index of the First 100 Seconds of Sleep Can Be a Reliable Scoring Method for Electrographic Status Epilepticus in Sleep.

Introduction: Electrical status epilepticus in sleep (ESES) is an electrographic pattern in which interictal epileptiform activity is augmented by the transition to sleep, with non-rapid eye movement sleep state characterized by near-continuous lateralized or bilateral epileptiform discharges. The aim of this study was to measure the reliability of the spike-wave index (SWI) of the first 100 seconds of sleep as a tool for the diagnosis of ESES.

Methods: One hundred forty studies from 60 unique patients met the inclusion.

Electroencephalography Technologist Inter-rater Agreement and Interpretation of Pediatric Critical Care Electroencephalography.

Objectives: Electroencephalography (EEG) technologists commonly screen continuous EEG. Until now, the inter-rater agreement or sensitivity for important EEG findings has been unknown in this group.

Methods: Twenty-nine EEG technologists and three clinical neurophysiologists interpreted 90 five-minute samples of pediatric critical care EEG.

Compliance With Standard Therapies and Remission Rates After Implementation of an Infantile Spasms Management Guideline.

Background: We implemented an infantile spasms management guideline recommending standard therapies and, early start of next treatment. After six years, we determined (1) our compliance with standard therapies, (2) time to next treatment, and (3) rate of initial and three-month electroclinical remission with first, second, and third treatments.

Methods: This is a retrospective record review of newly diagnosed spasms from September 2012 to September 2018, with the onset age of two months to two years.