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Previous research may have focused more on the direct rather than indirect effects of psychological characteristics on student success. This study explored the mediating effect of psychological sense of community and the moderating effect of growth mindset on the impacts of institutional integrity and perceived teacher support on student thriving in academic, interpersonal, and psychological domains. The hypothesized research model was proposed based on the Thriving Model, and the study was carried out in the setting of private universities in China. This study employed a partial least squares structural equation modeling (PLS-SEM) approach, obtaining a total of 1792 valid questionnaire responses through an online survey. The research highlights that psychological sense of community plays a crucial role in mediating the impact of institutional integrity and perceived teacher support on student thriving. In addition, it was found that growth mindset positively moderates the impact of institutional integrity and perceived teacher support on student thriving. Some implications and recommendations for teachers, administrators, and researchers in relevant fields were provided.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687743 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0312338 | PLOS |
Wounds
August 2025
Department of Nursing, Federal University of Ceará, Ceará, Brazil.
Background: Diabetic foot ulcers (DFUs) are a major clinical challenge, particularly among patients with refractory ulcers, that often lead to severe complications such as infection, amputation, and high mortality. Innovations supported by strong clinical evidence have the potential to improve healing outcomes, enhance quality of life, and reduce the economic burden on individuals and health care systems.
Objective: To describe the design of the concurrent optical and magnetic stimulation (COMS) therapy Investigational Device Exemption (IDE) study for refractory DFUs (MAVERICKS) trial.
Neuropsychopharmacol Rep
September 2025
Department of Behavioral Medicine, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Japan.
Masataka et al.'s cannabis gateway study misrepresents the 43.8% probability of cannabis users transitioning to illegal drugs as "rare," and misuses regression via the Table 2 Fallacy.
View Article and Find Full Text PDFJ Neurotrauma
September 2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Mean apparent propagator MRI (MAP-MRI) quantifies subtle alterations in tissue microstructure noninvasively and provides a more nuanced and comprehensive assessment of tissue architectural and structural integrity compared with other diffusion MRI techniques. We investigate the sensitivity of MAP-MRI-derived quantitative imaging biomarkers to detect previously unseen microstructural damage in patients with mild traumatic brain injuries (mTBI), whose clinical scans otherwise appeared normal. We developed and validated an MAP-MRI data processing pipeline for analyzing diffusion-weighted images for use in healthy controls and mTBI patients whose longitudinal scans were obtained from the GE/NFL/mTBI MRI database.
View Article and Find Full Text PDFBrain Res
September 2025
Institute of Zoology, Chinese Academy of Sciences, Beijing, China. Electronic address:
The blood-brain barrier (BBB) plays a pivotal role in safeguarding and sustaining the brain's microenvironment. Disruption of this barrier is commonly observed in various neurological disorders and is intricately linked with neuroinflammation. Rutin, a natural flavonoid known for its diverse biological activities, has showed protective effects against neuroinflammation.
View Article and Find Full Text PDFBiochim Biophys Acta Biomembr
September 2025
Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, Vienna, Austria.. Electronic address:
Using the stable synthetic analogue 3-aza-dehydroxylysyl-phosphatidylglycerol (3adLPG), the putative role of native staphylococcal LPG in inhibiting the antibiotic daptomycin from binding to its target phosphatidylglycerol (PG), was investigated with respect to interfacial interactions between these lipids, daptomycin, and calcium ions. The influence of lipid monolayer/bilayer composition and interfacial ion concentrations upon the structure and integrity of model membranes were probed after daptomycin challenge using a combination of surface x-ray scattering techniques and fluorescence assays. In models representing the membrane composition of the daptomycin susceptible phenotype consisting of PG/3adLPG in a 7:3 M ratio, calcium ions drive the formation of two separate phases; Ca cross-linked PG/PG pairs and PG/3adLPG ion pairs.
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