Publications by authors named "Rena A Li"

Background: Loss of nipple-areola complex (NAC) sensation following mastectomy is a significant concern in both gender-affirming and oncologic breast surgery. Targeted nipple-areola complex reinnervation (TNR) has emerged as a technique to improve sensory outcomes by restoring nerve connections to the NAC. This study systematically reviews the literature and conducts a meta-analysis to evaluate the efficacy of TNR in both gender-affirming mastectomy and oncologic breast reconstruction.

View Article and Find Full Text PDF

Skin aging leads to changes such as dyschromia, rhytids, dermal atrophy, and reduced elasticity. Adipose-derived cell therapies (ADCTs), including stromal vascular fraction (SVF), adipose-derived stem cells (ADSCs), and adipose-derived mesenchymal stem cells (AD-MSCs), have gained attention for their regenerative potential. In this systematic review, the authors aim to evaluate the effectiveness of ADCT in improving skin quality such as elasticity, texture, pigmentation, and rhytid reduction.

View Article and Find Full Text PDF

Background: Phenotypic variations in lower eyelid anatomy across ancestral groups significantly influence aesthetic and functional outcomes in oculoplastic surgery. Differences in skin thickness, fat distribution, muscle morphology, and bony architecture necessitate population-specific surgical strategies to optimize results and minimize complications.

Methods: A narrative review was conducted synthesizing anatomic and clinical data pertaining to lower eyelid structures across Asian, European, African, and Latin American ancestral groups.

View Article and Find Full Text PDF

Background: Patients increasingly rely on online resources for rhinoplasty education, yet the readability and reliability of these materials remain inconsistent. This systematic review and meta-analysis evaluated the quality and accessibility of online rhinoplasty-related patient education materials using DISCERN scores for reliability and Flesch-Kincaid Grade Level for readability.

Methods: A systematic search identified 12 studies analyzing 882 websites and 259 videos.

View Article and Find Full Text PDF

Renal disease, including chronic kidney disease (CKD) and end-stage renal disease (ESRD), has a profound impact on wound healing. Multiple studies have demonstrated that renal disease leads to an increased risk of diabetic foot ulcers, the formation of unique wounds like calciphylaxis, slower wound healing and a higher risk of amputation. This review details the interrelated mechanisms by which renal disease impacts wound healing.

View Article and Find Full Text PDF

Osteomyelitis remains a difficult-to-treat bone infection due to its high recurrence risk, complex surgical demands, and rising rates of multidrug-resistant organisms. While conventional treatments rely heavily on antibiotic-loaded materials, bioactive glass S53P4 offers a dual-action alternative, combining bacteriostatic and bactericidal activity with bone regenerative potential. A systematic review and meta-analysis following PRISMA guidelines was conducted to evaluate the clinical efficacy and safety of S53P4 bioactive glass in osteomyelitis treatment.

View Article and Find Full Text PDF

Occipital neuralgia (ON) is a debilitating craniofacial pain disorder often refractory to conservative treatments. Nerve decompression surgery has emerged as a promising intervention, yet the long-term efficacy and optimal patient selection remain unclear. This systematic review and meta-analysis evaluate the effectiveness of occipital nerve decompression in reducing pain frequency, intensity, and duration in patients with ON.

View Article and Find Full Text PDF

Background: Skin cancer patients who undergo Mohs surgery may require subsequent reconstructive rhinoplasty for large nasal defects. Autologous cartilage is the primary source of supporting cartilage grafts, but carries the risk of potential donor-site complications. In this study, we demonstrate the safety and efficacy of nonterminally irradiated fresh frozen human costal cartilage allografts (CCAs) in reconstructive rhinoplasty after skin cancer removal.

View Article and Find Full Text PDF

Background: Patients access online resources for information about various treatment modalities, including gender-affirming surgery (GAS) patient populations. The present study provides a readability, content quality, technical quality, and qualitative characteristic assessment of online patient educational materials (OPEM) related to GAS.

Methods: An online search using search phrases related to GAS was performed.

View Article and Find Full Text PDF

Introduction: Gender-affirming surgeries significantly improve the well-being of transgender and gender-diverse individuals. However, patients often rely on online patient education materials (OPEMs) to navigate surgical options, making readability, quality, and accessibility critical factors in informed decision-making.

Objective: The objective of this study is to evaluate the readability, quality, and accessibility of online patient education materials related to gender-affirming surgeries.

View Article and Find Full Text PDF

Introduction: Scarring significantly impacts patient quality of life, yet traditional assessments often rely on subjective evaluations, resulting in variability in predictions. This study aimed to evaluate the predictive accuracy of a Smart Image Analysis ChatGPT model in forecasting scar characteristics.

Methods: This single-institution prospective cohort study included 40 patients who underwent plastic surgery.

View Article and Find Full Text PDF

Patient-specific implants (PSIs) are increasingly used in craniomaxillofacial (CMF) surgery, but their advantages over stock plates in long-term outcomes remain unclear. This systematic review and meta-analysis compared PSIs and stock plates in 4 surgical categories: mandibular reconstruction, non-cleft orthognathic surgery, cleft orthognathic surgery, and mandibular fractures. A systematic search of PubMed, Embase, and Scopus identified comparative studies reporting quantitative outcomes.

View Article and Find Full Text PDF

Background: Nerve transfers have been proposed solutions for urinary, bowel, and genital dysfunction after spinal cord injury (SCI). However, there remains a need to characterize nerve candidates and other treatment variables for SCI. The objective of this systematic review was to characterize nerve transfer strategies and outcomes for the restoration of bladder, bowel, genital, and lower extremity function after SCI.

View Article and Find Full Text PDF

ObjectiveTo evaluate the readability of online patient education materials (PEMs) for cleft lip and/or palate and assess their alignment with recommended readability levels.DesignThis study is a systematic review and meta-analysis.SettingLiterature search conducted in PubMed, Scopus, and Embase databases following PRISMA guidelines.

View Article and Find Full Text PDF

Background: Asian blepharoplasty, or double eyelid surgery, is widely accepted among Asians; however, personal and cultural influences on patient satisfaction remain underexplored. This study examines the sociocultural and psychological factors shaping patient-reported outcomes through qualitative and quantitative analyses.

Methods: This mixed-methods study included 40 Asian-identifying women recruited via social media and community events.

View Article and Find Full Text PDF

Disparities in healthcare access and outcomes are well documented among racial and ethnic minority groups in the USA, with American Indian/Alaska Native (AI/AN) women experiencing significant barriers to postmastectomy breast reconstruction. This systematic review and meta-analysis of 11 studies highlights these disparities, revealing that AI/AN women are significantly less likely to undergo reconstruction compared with non-Hispanic white women (pooled OR 0.47, 95% CI 0.

View Article and Find Full Text PDF

This historical narrative presents a comprehensive historical journey delving into the diverse facets of gender identity and expression across ancient cultures. It explores these civilizations' perspectives on gender diversity, highlighting instances that challenged conventional gender norms. Transitioning to the modern era, the narrative examines the dynamic landscape of LGBTQ+ and trans movements, spotlighting influential figures whose advocacy has significantly influenced societal perceptions and advanced the rights of gender diverse individuals.

View Article and Find Full Text PDF