Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The digital transformation of pathology, through automation and computational tools, addresses current challenges in the field. This study evaluates Paige Pan Cancer, a novel artificial intelligence tool based on the Virchow foundation model, designed to flag invasive cancer in haematoxylin and eosin-stained slides from 16 primary tissue types. Using 62 cases from the Ipatimup Pathology Laboratory, we found the tool had a sensitivity of 93.3% and specificity of 87.5% in biopsies, and 94.7% sensitivity and 75.0% specificity in resections. Overall accuracy was 90.3%. Despite some misclassifications, Paige Pan Cancer demonstrates high sensitivity as a multi-organ screening tool in clinical practice.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00428-024-03988-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Toward Human-Centered Artificial Intelligence for Users' Digital Well-Being: Systematic Review, Synthesis, and Future Directions.
JMIR Hum Factors
September 2025
Seidenberg School of Computer Science and Information Systems, Pace University, New York City, NY, United States.
Background: As information and communication technologies and artificial intelligence (AI) become deeply integrated into daily life, the focus on users' digital well-being has grown across academic and industrial fields. However, fragmented perspectives and approaches to digital well-being in AI-powered systems hinder a holistic understanding, leaving researchers and practitioners struggling to design truly human-centered AI systems.
Objective: This paper aims to address the fragmentation by synthesizing diverse perspectives and approaches to digital well-being through a systematic literature review.
Parasitology of the twenty-first century: are we moving in the right direction?
J Med Microbiol
September 2025
Alberta Precision Laboratories Public Health Lab, Edmonton, Alberta, Canada.
For thousands of years, parasitic infections have represented a constant challenge to human health. Despite constant progress in science and medicine, the challenge has remained mostly unchanged over the years, partly due to the vast complexity of the host-parasite-environment relationships. Over the last century, our approaches to these challenges have evolved through considerable advances in science and technology, offering new and better solutions.
View Article and Find Full Text PDFArtificial Intelligence in cancer risk assessment of oral potentially malignant disorders: applications and challenges.
Int J Surg
September 2025
Department of Oral and Maxillofacial Surgery, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, China.
Comment on "The revolutionary impact of artificial intelligence in orthopedics: comprehensive review of current benefits and challenges".
J Robot Surg
September 2025
Department of CSE, United Institute of Technology, Coimbatore, India.
Global challenges in diabetes research and care: which way forward? An appraisal from the EASD Global Council.
Diabetologia
September 2025
Department of Diabetology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
This review article, developed by the EASD Global Council, addresses the growing global challenges in diabetes research and care, highlighting the rising prevalence of diabetes, the increasing complexity of its management and the need for a coordinated international response. With regard to research, disparities in funding and infrastructure between high-income countries and low- and middle-income countries (LMICs) are discussed. The under-representation of LMIC populations in clinical trials, challenges in conducting large-scale research projects, and the ethical and legal complexities of artificial intelligence integration are also considered as specific issues.
View Article and Find Full Text PDF