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http://dx.doi.org/10.1542/peds.2024-069114LE | DOI Listing |
PLoS One
September 2025
Institute of Primary Care, University Hospital of Zurich, Zurich, Switzerland.
Background: In sports science, freestyle swimming has been thoroughly studied for particular performance-related factors. Nonetheless, it is unknown what countries the top freestyle swimmers are from, especially not for age group swimmers. In addition, the existing research on the performance of master freestyle swimmers has yet to confirm that male swimmers achieve faster times than their female counterparts across all age groups and distances.
View Article and Find Full Text PDFBiomed Pharmacother
September 2025
Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Shijiazhuang, Hebei, China; Key Laboratory of Clinical Neurology, Ministry of Education, Hebei Medical University, Shijiazhuang, Heb
Myelin is a lipid-rich substance that is crucial for neural function. Neonatal anesthesia has been linked to neurological impairments associated with myelination dysfunction. This study sought to evaluate whether disrupted fatty acid homeostasis is involved in the mechanism of sevoflurane developmental neurotoxicity.
View Article and Find Full Text PDFCell Rep
September 2025
International Joint Laboratory for Drug Target of Critical Illnesses, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China; Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address:
Neurons that encode odor information are fundamental to innate fear processes, yet how mitral/tufted (M/T) cells encode innate fear remains unknown. Here, we identify three different response patterns of M/T cells in the dorsal olfactory bulb (dOB) during active avoidance elicited by non-dehydrogenated 2,4,5-trimethylthiazole (nTMT) through in vivo calcium imaging and multielectrode recordings in mice, including enhanced responses, suppressed responses, and no response. Remarkably, suppressed response M/T cells encode active avoidance, whereas suppressed and enhanced response M/T cells jointly encode passive freezing.
View Article and Find Full Text PDFEpilepsia
September 2025
Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
The rate of sudden unexpected death in epilepsy (SUDEP) is ~1 per 1000 patients each year. Terminal events reportedly involve repeated and prolonged apnea, suggesting a failure to autoresuscitate. To better understand the mechanisms and identify novel therapeutics, standardized tests to screen for autoresuscitation efficacy are needed in preclinical SUDEP.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
September 2025
Department of Biological Sciences, Clemson University, Clemson, SC, USA; Clemson University Center for Human Genetics, Greenwood, SC, USA. Electronic address:
Tetrabromobisphenol A (TBBPA), a widely used flame retardant in textiles and electronics, poses toxicological risks through both environmental and indoor exposures. Biomonitoring studies have detected significant TBBPA levels in prenatal environments, including cord blood, raising concerns about developmental impacts. Using zebrafish as a model, this study addresses critical gaps in understanding how developmental TBBPA exposures perturb regulatory pathways that govern dorsoventral patterning.
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