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The accurate prediction of vehicle behavior is crucial for autonomous driving systems, impacting their safety and efficiency in complex urban environments. To address the challenge of multi-agent trajectory prediction, we propose a novel model integrating multiple input modalities, including historical trajectories, map data, vehicle features, and interaction information. Our approach employs a Conditional Variational Autoencoder (CVAE) framework with a decoder that predicts control actions using the Gaussian Mixture Model (GMM) and then converts these actions into dynamically feasible trajectories through a bicycle model. Evaluated on the nuScenes dataset, the model achieves great performance across key metrics, including minADE of 1.26 and minFDE of 2.85, demonstrating robust performance across various vehicle types and prediction horizons. These results indicate that integrating multiple data sources, physical models, and probabilistic methods significantly improves trajectory prediction accuracy and reliability for autonomous driving. Our approach generates diverse yet realistic predictions, capturing the multimodal nature of future outcomes while adhering to Physical Constraints and vehicle dynamics.
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http://dx.doi.org/10.3390/s24227323 | DOI Listing |
Crit Care
September 2025
Department of Pediatrics I, University Hospital Essen, University of Duisburg-Essen, Hufelandstr, 55, Essen, 45239, Germany.
Background: Gender disparities persist in medical research. This study assessed gender representation trends in first and senior authorships in the five highest-ranked critical care journals (by impact factor) over a 20-year period.
Methods: We analyzed author gender distribution from 2005 to 2024.
Addict Behav
September 2025
Key Laboratory of Basic Research and Health Management on Chronic Diseases in Heilongjiang Province, Harbin Medical University, Daqing Campus, Xinyang Street 39, 163319 Daqing, Heilongjiang, China. Electronic address:
Extensive research has documented the deleterious developmental effects of problematic mobile phone use (PMPU) on emerging adults. However, in collectivistic cultures, few studies have investigated the longitudinal trend of PMPU of emerging adults and its associated environmental and individual factors. This study tracked 1,179 first-year undergraduates (67.
View Article and Find Full Text PDFJ Psychiatr Res
September 2025
Laboratory of Biological Psychiatry, Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, Tianjin, 300222, China. Electronic address:
Background: The duration of untreated psychosis (DUP) is a critical factor influencing long-term outcome in schizophrenia (SCZ). Its short-term effects during early treatment remain less well characterized.
Methods: We enrolled 300 drug-naïve SCZ patients, of whom 78 completed a 12-week evaluation with comprehensive clinical and functional assessments.
PLoS One
September 2025
Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Background: Stroke is a leading cause of death and disability globally, with frequent cognitive sequelae affecting up to 60% of stroke survivors. Despite the high prevalence of post-stroke cognitive impairment (PSCI), early detection remains underemphasized in clinical practice, with limited focus on broader neuropsychological and affective symptoms. Stroke elevates dementia risk and may act as a trigger for progressive neurodegenerative diseases.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Capturing the dynamic changes in patients' internal states as they approach death due to fatal diseases remains a major challenge in understanding individual pathologies and improving end-of-life care. However, existing methods primarily focus on specific test values or organ dysfunction markers, failing to provide a comprehensive view of the evolving internal state preceding death. To address this, we analyzed electronic health record (EHR) data from a single institution, including 8,976 cancer patients and 77 laboratory parameters, by constructing continuous mortality prediction models based on gradient-boosting decision trees and leveraging them for temporal analyses.
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