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One of the most common reasons a patient would see an otolaryngologist is for nasal obstruction. This article provides an overview of the physical principles related to nasal airflow as well as the critical role that the internal nasal valve plays in regulating airflow resistance. Common treatment options for internal nasal valve obstruction are discussed as well as an in-depth tutorial on an alternate lateral nasal suspension suture technique for internal nasal valve collapse.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11592332 | PMC |
http://dx.doi.org/10.3390/bioengineering11111138 | DOI Listing |
J Vis
September 2025
Neuroscience Program, Western University, London, ON, Canada.
Studies of visual face processing often use flat images as proxies for real faces due to their ease of manipulation and experimental control. Although flat images capture many features of a face, they lack the rich three-dimensional (3D) structural information available when binocularly viewing real faces (e.g.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Rationale: Extranodal natural killer (NK)/T-cell lymphoma is an uncommon non-Hodgkin lymphoma, prevalent in Asia. It often involves the nasal and upper airway regions but can disseminate to other sites like skin, soft tissue, testis, and gastrointestinal tract, characterized by Epstein-Barr virus association.
Patient Concerns: This report discusses a 48-year-old male initially diagnosed with Behcet syndrome with dry mouth, uveitis, pruritic macules, and human leukocyte antigen-B51 positivity.
BMJ Case Rep
September 2025
Hematology/Oncology, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA.
Extranodal natural killer/T-cell lymphoma (ENKTCL), nasal type, is a rare and aggressive subtype of non-Hodgkin's lymphoma that often presents with extranodal involvement. While relapse patterns commonly involve the nasal cavity, lungs or skin, cardiac involvement is rare. We report a late 50-year-old patient with ENKTCL, nasal type, who achieved complete remission following chemotherapy and autologous stem cell transplantation.
View Article and Find Full Text PDFEar Nose Throat J
September 2025
Department of Otolaryngology-Head and Neck Surgery, OU Health, University of Oklahoma Health Sciences Center, OK, USA.
Epithelioid hemangioendothelioma (EHE) is an exceptionally rare vascular tumor with an incidence of <1/million people/year. This case report describes a patient who initially presented with progressive left-sided neck swelling and dysphagia and was found to have EHE at the confluence of the left subclavian and internal jugular veins. Diagnosis was confirmed with a core needle biopsy after an initial inconclusive fine-needle aspiration.
View Article and Find Full Text PDFJ Nutr Health Aging
September 2025
Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom; Department of Pathophysiology and Transplantation, Università Degli Studi di Milano, Via Francesco Sforza, 35, 20122 Milan, Italy; Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Angelo Bia
Introduction: The gut-liver axis regulates metabolic homeostasis, with bile acids (BAs) serving as key signalling molecules. BA dysregulation is implicated in metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction- and alcohol-associated liver disease (MetALD), yet consistent identification of BA markers and their mechanistic roles across different stages of these diseases remain elusive.
Methods: We integrated three complementary studies to examine BA dysregulation: a population-based cohort (1522 females from TwinsUK with serum BA and liver biomarker data), a clinical cohort (30 patients with steatotic liver disease, fibrosis stages F0-F4, and 4 controls), and rodent models (20 rats with MASLD/MetALD vs.