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The use of wearable assistive devices is growing in both industrial and medical fields. Combining human expertise and artificial intelligence (AI), e.g., in human-in-the-loop-optimization, is gaining popularity for adapting assistance to individuals. Amidst prevailing assertions that AI could surpass human capabilities in customizing every facet of support for human needs, our study serves as an initial step towards such claims within the context of human walking assistance. We investigated the efficacy of the Biarticular Thigh Exosuit, a device designed to aid human locomotion by mimicking the action of the hamstrings and rectus femoris muscles using Serial Elastic Actuators. Two control strategies were tested: an empirical controller based on human gait knowledge and empirical data and a control optimized using Reinforcement Learning (RL) on a neuromuscular model. The performance results of these controllers were assessed by comparing muscle activation in two assisted and two unassisted walking modes. Results showed that both controllers reduced hamstring muscle activation and improved the preferred walking speed, with the empirical controller also decreasing gastrocnemius muscle activity. However, the RL-based controller increased muscle activity in the vastus and rectus femoris, indicating that RL-based enhancements may not always improve assistance without solid empirical support.
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http://dx.doi.org/10.3390/biomimetics9110665 | DOI Listing |
Dev Psychobiol
September 2025
Department of Psychiatry, University of Illinois Chicago, Chicago, Illinois, USA.
Depressed mothers often experience parenting difficulties, which can persist after their symptoms have remitted. However, not all depressed mothers show parenting struggles, suggesting that there could be unidentified characteristics that increase risk. Specifically, neurobiological models emphasize that reward system deficits contribute to maladaptive parenting and depression, but no studies have evaluated how they could conjointly lead to parenting challenges.
View Article and Find Full Text PDFNat Commun
September 2025
Animal Physiology Unit, Institute of Neurobiology, University of Tübingen, Tübingen, Germany.
Interval timing, the ability to perceive and estimate durations between events, is essential for many animal behaviors. In mammals, it is linked to specific cortical and sub-cortical brain regions, but its neural basis in birds remains unclear. We trained two male carrion crows on a time estimation task using visual stimuli, cueing them to wait for a minimum duration of 1500 ms, 3000 ms, or 6000 ms before responding to receive a reward.
View Article and Find Full Text PDFBMJ Lead
September 2025
Green Templeton College, University of Oxford, Oxford, UK.
Background: In 2021, Dr Kalra embraced an opportunity for a leadership role at a start-up healthcare organisation in India. This gave him an opportunity to adapt his National Health Service (NHS) leadership experience to the evolving Indian private healthcare landscape. This paper shares his lived experience as a National Medical Director and delves into the experiences and leadership insights he acquired during this.
View Article and Find Full Text PDFJ Safety Res
September 2025
University of Massachusetts Amherst, 160 Governors Drive, Amherst, MA 01002, USA. Electronic address:
Introduction: Effective driver education for teen drivers is increasingly important, especially as Advanced Driver Assistance Systems (ADAS) become standard in modern vehicles. This study examines driver education programs in the commonwealth of Massachusetts and explores how they are placed to prepare young drivers to understand and safely use ADAS technologies.
Method: Through a convergent mixed-methods approach, we analyzed thematic data from interviews and surveys of key stakeholders and performed sentiment analysis to capture their concerns and attitudes.
Int J Med Inform
September 2025
Profesora Titular de la Universidad de Alicante, Spain. Electronic address:
Background: Immersive Virtual Reality (IVR) is increasingly used in health sciences education to simulate high-risk, low-frequency scenarios such as mass casualty incidents. While prior research has focused on student outcomes, the perceptions of instructors about available IVR tools remains underexplored.
Objective: To evaluate instructors' perceptions regarding ease of use, educational value, and technical quality of the "VR-Triage" immersive simulation tool in a disaster and mass casualty incident course.