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Intelligent Transportation Systems (ITS) are essential for modern urban development, with urban flow prediction being a key component. Accurate flow prediction optimizes routes and resource allocation, benefiting residents, businesses, and the environment. However, few methods address the spatial-temporal heterogeneity of urban flows. Existing methods typically capture spatial features solely from urban flows, but spatial feature sensitivity becomes a bottleneck when dealing with small or noisy datasets. To address this issue, we propose a method for urban flow prediction via mutual reinforcement with multi-scale regional information (MR-UFP). Firstly, we employ spatial-temporal random masking and spatial-temporal contrastive learning pre-training to directly mine spatial-temporal heterogeneity from historical flow data. Secondly, we transform the task of spatial feature extraction and embedding for urban flow prediction into a mutual reinforcement task by multi-scale region classification auxiliary task. The adaptive environment fusion module and real-time graph processing dynamically correlate regional and environmental features during flow prediction. To balance the mutual reinforcement of the two tasks, we design a joint loss function to optimize feature embedding and feedback correction, ensuring robust and accurate urban flow prediction. Extensive experiments on two real-world datasets demonstrate that MR-UFP outperforms baseline models, showcasing its robustness and effectiveness even with minimal data.
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http://dx.doi.org/10.1016/j.neunet.2024.106900 | DOI Listing |
Med Eng Phys
October 2025
Ansys Inc., Houston, TX 77094, USA.
Introduction: Benchtop and animal models have traditionally been used to study the propagation of Onyx Liquid Embolic Systems (Onyx) used in the treatment of brain arteriovenous malformations (AVM). However, such models are costly, do not provide sufficient detail to elucidate how variations in Onyx viscosity alter flow dynamics, and rely on some trial-and-error, resulting in elongated timelines for product development.
Objectives: The goal of this study was to leverage Computational Fluid Dynamics (CFD) simulations to predict the behavior of different Onyx formulations.
Soc Sci Med
September 2025
Department of Sociology and Criminology, State University of New York at Buffalo, 430 Park Hall, USA.
As the prevalence of Alzheimer's disease and related dementias (ADRD) rises in the United States, understanding social determinants of cognitive health has become increasingly important. While a robust literature highlights the downward transmission of (dis)advantage across generations, emerging research suggests that this transmission may also flow upwards from offspring to parents. Drawing on data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) parent sample, we examine the association between adult children's educational attainment and parental cognitive functioning at midlife using a propensity score matching approach to account for selection on observed confounders.
View Article and Find Full Text PDFPLoS One
September 2025
Center for Radiological Research, Columbia University Irving Medical Center, New York, New York, United States of America.
In the event of a large-scale radiological or nuclear emergency, a rapid, high-throughput screening tool will be essential for efficient triage of potentially exposed individuals, optimizing scarce medical resources and ensuring timely care. The objective of this work was to characterize the effects of age and sex on two intracellular lymphocyte protein biomarkers, BAX and p53, for early radiation exposure classification in the human population, using an imaging flow cytometry-based platform for rapid biomarker quantification in whole blood samples. Peripheral blood samples from male and female donors, across three adult age groups (young adult, middle-aged, senior) and a juvenile cohort, were X-irradiated (0-5 Gy), and biomarker expression was quantified at two- and three-days post-exposure.
View Article and Find Full Text PDFJ Neurooncol
September 2025
Division of Neurosurgery, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Tottori, Japan.
Purpose: This study aimed to evaluate the prognostic significance of microvessel density (MVD), assessed by CD34 immunohistochemistry (IHC), and its correlation with radiological features and bevacizumab (BEV) treatment efficacy in newly diagnosed glioblastoma.
Methods: We retrospectively analyzed 41 patients with newly diagnosed glioblastoma. MVD was quantified using CD34 IHC, and patients were stratified into low and high MVD groups according to the cutoff value determined by receiver operating characteristic curve analysis (sensitivity, 76.
Clin Res Cardiol
September 2025
Department of (Interventional) Cardiology, Thoraxcenter, Erasmus University Medical Center, Room Rg-628, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
Background: Fractional flow reserve (FFR) for non-culprit lesions (NCLs) in patients with ST-elevation myocardial infarction (STEMI) can be influenced by temporary changes in microvascular resistance. Angiography-derived vessel fractional flow reserve (vFFR) has been tested as a less-invasive alternative.
Aims: The FAST STEMI II study aimed to assess the diagnostic performance of acute-setting vFFR vs.