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The inhibitory effect of chronic psychological stress on reproductive behavior is widely recognized since long. However, the biological mechanisms underlying these effects, especially the cellular biology of the testicular cells, have not been fully investigated. This study aimed to investigate the effects of chronic psychological stress on rat reproductive behavior and its correlation with testicular cell damage and oxidative stress. The results showed that chronic psychological stress led to a decline in the preference scores of male rats for female rats and caused damage to the testicular tissue structure. Subcellular structures were particularly affected in the chronic psychological stress rats. Furthermore, the levels of MDA, NO, and NOS in testicular cells substantially increased under chronic psychological stress conditions. In conclusion, male reproductive behavioral disorders induced by chronic psychological stress are potentially linked to oxidative damage in testicular tissue.
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http://dx.doi.org/10.1016/j.repbio.2024.100934 | DOI Listing |
Behav Brain Res
September 2025
Department of Pharmacology, Smt. Kishoritai Bhoyar College of Pharmacy, New Kamptee, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, MS 441 002, India. Electronic address:
Alcohol Use Disorder (AUD) is a major global health challenge characterized by the recurrence of alcohol consumption, withdrawal symptoms, and significant social, economic, and health-related burdens. Despite conventional treatments such as cognitive behavioral therapy and medications like disulfiram and naltrexone, the majority of patients do not achieve adequate relief due to the multifactorial nature of this disorder, including mental health issues and neuroadaptive changes. Recent studies demonstrated that chronic alcohol consumption results in the disruption of both the production and signaling of endogenous agmatine, a neuromodulator synthesized from L-arginine.
View Article and Find Full Text PDFNeurol Ther
September 2025
Department of Neurology, Neurocritical Care, and Neurorehabilitation, Christian Doppler University Hospital, Centre for Cognitive Neuroscience, Paracelsus Medical University, Member of ERN EpiCARE, 5020, Salzburg, Austria.
Introduction: Migraine headache not only is associated with high levels of suffering but also represents a considerable socioeconomic challenge. It is linked to various psychological and physiological impairments, including sensorimotor and somatosensory dysfunction, like those observed in other persistent pain syndromes. This study aims to determine whether individuals with high-frequency episodic (HFEM) or chronic migraine (CM) exhibit differences in somatosensory perception compared to healthy individuals and to explore potential correlations with neuropsychological features.
View Article and Find Full Text PDFAsian Nurs Res (Korean Soc Nurs Sci)
September 2025
School of Nursing, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China; The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China. Electronic address:
Purpose: Maintenance hemodialysis (MHD) patients frequently experience psychological distress, including learned helplessness(LH), which impairs self-management and adversely affects health-related quality of life. This study aimed to investigate the latent profiles of LH among MHD patients and to identify the bio-psycho-social determinants influencing these profiles.
Method: A cross-sectional survey was conducted in five hospitals in Guangdong, China, from May to July 2024, enrolling 548 MHD patients.
JMIR Public Health Surveill
September 2025
Public Health Research Group, Department of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, CIBER of Epidemiology and Public Health, Alicante, Spain.
Background: Content creators (CCs), like any other worker, are exposed to various occupational hazards that can affect their physical, mental, and social well-being, with psychosocial and ergonomic risks being particularly relevant. The combination of prolonged work hours, sedentary lifestyles, excessive public scrutiny, and often job insecurity and unpredictability (manifested as continuous connectivity and anticipation of sporadic tasks) presents a significant risk for the development of health issues.
Objective: This study reviews the scientific literature to identify the potential pathological processes affecting CCs on social media.
Health Psychol Rev
September 2025
Department of Psychological Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Beliefs about illness powerfully shape how people experience and respond to health conditions. The dominant theory underpinning illness perception - Leventhal's Common-Sense Model - proposes that individuals construct cognitive representations of illness based on specific beliefs about its features and likely course (e.g.
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