Latent Profile Analysis and Influencing Factors of Learned Helplessness in Maintenance Hemodialysis Patients: A Cross-sectional Study.

Purpose: Maintenance hemodialysis (MHD) patients frequently experience psychological distress, including learned helplessness(LH), which impairs self-management and adversely affects health-related quality of life. This study aimed to investigate the latent profiles of LH among MHD patients and to identify the bio-psycho-social determinants influencing these profiles.

Method: A cross-sectional survey was conducted in five hospitals in Guangdong, China, from May to July 2024, enrolling 548 MHD patients.

Acupoint stimulation methods for premature ovarian insufficiency: a systematic review and network meta-analysis of randomized controlled trials.

Objective: The aims of this study were to evaluate and rank the efficacy of different acupoint stimulation (AS) therapies in the treatment of premature ovarian insufficiency (POI) by network meta-analysis (NMA) and to explore the optimal AS regimen for improving sex hormone levels and clinical symptoms.

Methods: Randomized controlled trials (RCTs) in English and Chinese up to November 2024 were searched in eight databases, including the Cochrane Library, PubMed, and the China National Knowledge Infrastructure (CNKI). Included studies were patients with POI diagnosed according to established international or Chinese guidelines.

The clinical value of neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR) and systemic inflammation response index (SIRI) for predicting the occurrence and severity of pneumonia in patients with intracerebral hemorrhage.

Background: Inflammatory mechanisms play important roles in intracerebral hemorrhage (ICH) and have been linked to the development of stroke-associated pneumonia (SAP). The neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR) and systemic inflammation response index (SIRI) are inflammatory indexes that influence systemic inflammatory responses after stroke. In this study, we aimed to compare the predictive value of the NLR, SII, SIRI and PLR for SAP in patients with ICH to determine their application potential in the early identification of the severity of pneumonia.