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Population aging generated changes in the epidemiological profile and culminated in a high frequency of diseases. The objective of this study was estimating the prevalence of multimorbidity and the associated variables in the elderly of an educational program in the Federal District of Brazil. This is a cross-sectional study with data collection carried out during the period from December 2022 to April 2023 by means of telephone calls. Multimorbidity was defined as a concomitant presence of 2 or more noncommunicable chronic diseases. One-hundred fifty individuals aged between 60 and 82 years old participated in the study. The median number of self-reported diseases was 2, ranging from 0 to 9. The estimated prevalence of multimorbidity was 69.3%, being higher among elderly individuals self-reporting their health as regular or bad/or very bad, having systemic arterial hypertension, diabetes mellitus, dyslipidaemia, hypothyroidism, overweight/obesity, and depression, including polypharmacy (P < .05). The high rate of multimorbidity and associated variables shows the importance of an integrated approach on health services focused on promoting health and preventing health impairment to favor the quality of life during aging.
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http://dx.doi.org/10.1097/MD.0000000000040493 | DOI Listing |
JAMA Netw Open
September 2025
Critical Illness, Brain Dysfunction, and Survivorship Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Importance: Survivors of critical illness often have ongoing issues that affect functioning, including driving ability.
Objective: To examine whether intensive care unit (ICU) delirium is independently associated with long-term changes in driving behaviors.
Design, Setting, And Participants: This multicenter, longitudinal cohort study included 151 survivors of critical illness residing within 200 miles of Nashville, Tennessee.
Infect Dis Ther
September 2025
Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Introduction: Cognitive frailty (CF), which typically precedes dementia and functional decline, serves as a more robust predictor of adverse health outcomes compared to physical frailty alone, representing a critical challenge in promoting healthy aging among older people living with HIV (PLWH) aged ≥ 50 years. This study aimed to investigate the prevalence of cognitive frailty and identify its associated factors among PLWH aged ≥ 50 years.
Methods: A convenience sample of 344 PLWH ≥ 50 years was recruited from a tertiary Grade A hospital in Zunyi, China.
Exp Brain Res
September 2025
School of Information Science and Technology, Yunnan Normal University, Kunming, 650500, China.
This study explores how differences in colors presented separately to each eye (binocular color differences) can be identified through EEG signals, a method of recording electrical activity from the brain. Four distinct levels of green-red color differences, defined in the CIELAB color space with constant luminance and chroma, are investigated in this study. Analysis of Event-Related Potentials (ERPs) revealed a significant decrease in the amplitude of the P300 component as binocular color differences increased, suggesting a measurable brain response to these differences.
View Article and Find Full Text PDFBrain Struct Funct
September 2025
Department of Neurosurgery, Yeditepe University School of Medicine, Istanbul, Turkey.
The anterior commissure (AC) has an anterior and posterior limb. Despite comprehensive information about the posterior limb, there is limited and conflicting information about the anterior limb in the literature. We aimed to show the anatomical relationships of the AC with neighboring structures by using white matter microdissection and magnetic resonance (MR) tractography, primarily on the anterior limb of the AC.
View Article and Find Full Text PDFBrain Behav
September 2025
Radiology Department, Yantaishan Hospital, Yantai, Shandong, China.
Objective: To investigate the characteristics of brain structures in patients with noise-induced hearing loss (NIHL) using source-based morphometry (SBM) and to evaluate the correlation between abnormal brain regions and clinical data.
Methods: High-resolution 3D T1 structural images were acquired from 81 patients with NIHL and 74 age- and education level-matched healthy controls (HCs). The clinical data of all subjects were collected, including noise exposure time, monaural hearing threshold weighted values (MTWVs), Mini-Mental State Examination (MMSE), and Hamilton Anxiety Scale (HAMA) scores.