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This paper proposed a muscle-activation-dependent human-exoskeleton model for predicting human-exoskeleton coupling parameters to improve the studies of coupling dynamics. With a newly designed platform and the help of 20 volunteers (10 males and 10 females, age: 24.45 ± 2.31 years old, height: 167.70 ± 8.35 cm, weight: 66.50 ± 18.74 kg), coupling parameters were identified with surface electromyographic (EMG) signals monitored to represent muscle activation. Then convolutional neural network (CNN) was used to predict coupling parameters with six EMG features as inputs:mean absolute value (MAV), mean absolute value slope (MAVSLP), waveform length (WL), Willison Amplitude (WAMP), variance (VAR), and auto regressive (AR) coefficients. Finally, sensitivity analysis of the CNN's performance identified AR, MAV, and VAR as the key determinants of the coupling parameters. Further analysis unveiled strong correlation between coupling stiffness and both MAV and VAR. The novelty and contribution are the design of coupling experimental platform and the establishment of muscle-activation-dependent human-exoskeleton coupling model which provides a possibility to obtain coupling parameter identification form complex human-exoskeleton interaction scenarios.
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http://dx.doi.org/10.1016/j.jelekin.2024.102946 | DOI Listing |
Chembiochem
September 2025
Faculty of Biology and Biotechnology, Microbial Biotechnology, Ruhr University Bochum, Universitätsstrasse 150, Bochum, 44780, Germany.
The N-hydroxylating monooxygenase (NMO) TheA from Thermocrispum agreste catalyzes the N-hydroxylation step of l-ornithine, which is the first step in the thermochelin siderophore biosynthesis. Characterization of this enzyme revealed a significant thermostability up to 50 °C and activity with the non-native substrate d-ornithine with kinetic parameters (K = 4.06 ± 0.
View Article and Find Full Text PDFBrain Res Bull
September 2025
Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for the Developing Mind, Children's Hospital Los Angeles, Los Angeles, CA.
We propose a Biophysically Restrained Analog Integrated Neural Network (BRAINN), an analog electrical network that models the dynamics of brain function. The network interconnects analog electrical circuits that simulate two tightly coupled brain processes: (1) propagation of an action potential, and (2) regional cerebral blood flow in response to the metabolic demands of signal propagation. These two processes are modeled by two branches of an electrical circuit comprising a resistor, a capacitor, and an inductor.
View Article and Find Full Text PDFJ Chem Theory Comput
September 2025
Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24060, United States.
The Slater-type F12 geminal length scales originally tuned for the second-order Mo̷ller-Plesset F12 method are too large for higher-order F12 methods formulated using the SP (diagonal fixed-coefficient spin-adapted) F12 ansatz. The new geminal parameters reported herein reduce the basis set incompleteness errors (BSIEs) of absolute coupled-cluster singles and doubles F12 correlation energies by a significant─and increase with the cardinal number of the basis─margin. The effect of geminal reoptimization is especially pronounced for the cc-pVZ-F12 basis sets (specifically designed for use with F12 methods) relative to their conventional aug-cc-pVZ counterparts.
View Article and Find Full Text PDFTraffic Inj Prev
September 2025
School of Safety Engineering, Beijing Institute of Petrochemical Technology, Beijing, China.
Objective: To clarify the potential risks and causative mechanisms of glare from nighttime road fill lights on driving safety, this study investigates the dual interference of glare-induced visual cognitive load and physiological stress.
Methods: A field driving experiment involving 20 drivers was conducted, with real-time collection of visual data (e.g.
Phys Rev Lett
August 2025
National Astronomical Observatories, Chinese Academy of Sciences, A20 Datun Road, Chaoyang District, Beijing, 100101, Peoples Republic of China.
The Dark Energy Spectroscopic Instrument (DESI) is a massively parallel spectroscopic survey on the Mayall telescope at Kitt Peak, which has released measurements of baryon acoustic oscillations determined from over 14 million extragalactic targets. We combine DESI Data Release 2 with CMB datasets to search for evidence of matter conversion to dark energy (DE), focusing on a scenario mediated by stellar collapse to cosmologically coupled black holes (CCBHs). In this physical model, which has the same number of free parameters as ΛCDM, DE production is determined by the cosmic star formation rate density (SFRD), allowing for distinct early- and late-time cosmologies.
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