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Background Thoracic surgery patients face unique postoperative challenges, particularly those undergoing lung resections. This study aimed to identify common complications and their management within the 30-day postoperative period, as well as investigate the relationship between early postoperative complications and unplanned outpatient follow-ups. Methods A retrospective analysis was conducted on 947 patients who underwent thoracic surgery between January 2020 and December 2023. Of these, 168 patients who had unscheduled follow-ups were included in the final analysis. Results The most common surgical procedure was pulmonary resection (68.5%), with prolonged air leaks (19.6%) being the most frequent postoperative complication. Unplanned outpatient visits were primarily due to dyspnea (38.1%) and surgical site complications (33.9%). While the rate of readmission did not significantly differ between complication-free and complicated patients (p=0.070), patients with complications were 2.117 times more likely to be readmitted (p=0.044). Surgical technique impacted postoperative outcomes, with minimally invasive surgery associated with fewer complications and shorter hospital stays compared to open thoracotomy. Conclusion Our findings emphasize the need for tailored postoperative care and diligent follow-up, especially for patients at higher risk of readmission due to complications such as pneumothorax, empyema, and prolonged air leaks.
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http://dx.doi.org/10.7759/cureus.71190 | DOI Listing |
Ann Surg Oncol
September 2025
Department of Thoracic Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Gen Thorac Cardiovasc Surg
September 2025
Thoracic Surgery Department, Centre Hospitalier de la Cote Basque, 13, avenue de l'Interne Jacques Loeb, 64100, Bayonne, France.
Objective: Reduction of bleeding and prolonged air leak (>5 days) following major lung resection remains a challenge. Hemostasis and aerostasis devices can facilitate earlier pleural de-drainage and fast-track. Our objectives were to evaluate the efficacy of TenaTac (an elastic, adhering patch approved as a medical device) in reducing bleeding and prolonged air leak after major lung resection.
View Article and Find Full Text PDFCancer Immunol Immunother
September 2025
Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Objective: CircRNAs are involved in cancer progression. However, their role in immune escape in non-small cell lung cancer (NSCLC) remains poorly understood.
Methods: This study employed RIP-seq for the targeted enrichment of circRNAs, followed by Western blotting and RT-qPCR to confirm their expression.
Cancer Immunol Immunother
September 2025
Guangdong Provincial Clinical Research Center for Cancer, State Key Laboratory of Oncology in South China, Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangdong Esophageal Cancer Institute, Guangzhou, 510060, China.
Background: Previous studies indicated that over-dissection of lymph nodes might impair the efficacy of immunotherapy. This study aims to explore the prognostic value of ypN + status and the impact of lymph node dissection (LND) on survival after neoadjuvant immunochemotherapy (NICT) for esophageal squamous cell cancer (ESCC).
Methods: This double-center retrospective study enrolled 206 consecutive ESCC patients who underwent NICT followed by esophagectomy between 2018 and 2024.
Nat Genet
September 2025
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Aberrant DNA methylation has been described in nearly all human cancers, yet its interplay with genomic alterations during tumor evolution is poorly understood. To explore this, we performed reduced representation bisulfite sequencing on 217 tumor and matched normal regions from 59 patients with non-small cell lung cancer from the TRACERx study to deconvolve tumor methylation. We developed two metrics for integrative evolutionary analysis with DNA and RNA sequencing data.
View Article and Find Full Text PDF