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http://dx.doi.org/10.14309/ajg.0000000000002832 | DOI Listing |
Vet Ital
September 2025
Department of Biotechnology, Institute of Applied Sciences and Humanities, GLA University, Mathura, India.
Extracellular vesicles (EVs) are cell-derived and play a notable role in the development of chronic diseases and can be used as biomarkers as they transport microRNAs (miRNA). Existing research has found that most miRNA functions are carried out via intercellular transmission of EVs, which can protect and sort miRNAs. Early detection of disease is crucial for controlling the spread of the disease and improving livestock prognosis.
View Article and Find Full Text PDFData Brief
October 2025
Department of Computer Engineering, Jordan University of Science and Technology, P.O. Box 3030 Irbid 22110 Jordan.
Johne's disease (paratuberculosis), caused by subspecies , is a chronic intestinal infection that affects ruminants and poses significant challenges for livestock health and management. Accurate and early diagnosis is of paramount importance for effective disease control, yet traditional histopathological assessment requires expert interpretation and remains subject to interobserver variability. In this paper, we present a curated dataset of histopathological slide images collected from tissue samples confirmed to be positive or negative for Johne's disease.
View Article and Find Full Text PDFImmunobiology
August 2025
Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, China; The Fourth Affiliated Hospital of Soochow University, Suzhou 215123, China. Electronic address:
Cecal appendix is a unique niche for commensal bacteria, and has been considered the primary site for immunoglobulin A production. Yet its immune function in anti-infection immunity has not been fully understood. In order to elucidate whether cecal patch (CeP), the murine version of appendix, would influence the immune response induced by Mycobacterium tuberculosis (M.
View Article and Find Full Text PDFFish Shellfish Immunol
August 2025
Institute of Aquatic Biotechnology, College of Life Sciences, Qingdao University, Qingdao, Shandong, 266071, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao Marine Science and Technology Center, Qingdao, Shandong, 266237, China; Shandong Center of Technology Inn
Src homology region 2 domain-containing phosphatase-1 (SHP-1) is a vital negative regulator of immune cell signaling, yet its role in teleost early adaptive immune response remains poorly understood. Here, we investigated the regulatory role of SHP-1 in early adaptive immune response and the potential underlying mechanisms in Chinese tongue sole (10 ± 2 g and 10 ± 1 cm) infected with Mycobacterium marinum. In this study, SHP-1 expression was artificially manipulated by overexpression and inhibition following bacterial infection, and the former reduced mortality by 33.
View Article and Find Full Text PDFMicroorganisms
July 2025
Guangxi Laboratory on the Study of Coral Reefs in the South China Sea, Coral Reef Research Center of China, School of Marine Sciences, Guangxi University, Nanning 530004, China.
(SA) is a severe prevalent pathogen, resulting in high morbidity and mortality in the global tilapia industry. With increasing bacterial resistance to antibiotics, alternative strategies are urgently needed. This study aims to investigate the antibacterial activity and the underlying mechanisms of the natural product xanthohumol (XN) against SA infection in tilapia ().
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