Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
As natural polymers, Lactiplantibacillus plantarum exopolysaccharides (EPS) possess a wide range of bioactivities but suffer from low yields and unclear relationships between functional activity and structure. To this end, the chemical structure and bioactive properties of EPS from Lactiplantibacillus plantarum MY04 were investigated. As a result, three polysaccharide fractions (EPS-1, EPS-2, EPS-3) were separated and purified, of which EPS-2 had better antioxidant activity and α-glucosidase inhibitory ability. More importantly, EPS-2 can significantly enhance insulin sensitivity in HepG2 cells by upregulating enzyme activities in the glycolytic pathway and mitigating oxidative stress-induced damage. In addition, the structural characterization of EPS-2 was also comprehensively elucidated. It was found that EPS-2 was mainly composed of mannose with a molecular weight of 2.3 × 10 Da, and its main chain structure is →3)-Manp-(1 → 2)-Manp-(1 → 2,6)-Manp-(1 → 2,6)-Manp-(1→, providing a theoretical basis for understanding the relationship between structure and function of polysaccharides.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijbiomac.2024.137008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The ameliorative effect of Lactiplantibacillus plantarum SCS2 on DSS-induced murine colitis.
Arch Microbiol
September 2025
School of Public Health, Chengdu University of Traditional Chinese Medicine, No. 1166, Liutai Avenue, Wenjiang District, Chengdu, 611137, Sichuan Province, China.
The inhibitory effects of Lactiplantibacillus plantarum on inflammatory responses are known, but its action mechanisms in oxidative stress, immunomodulation, and intestinal homeostasis remain of interest. Accordingly, we investigated the protective effects of Lactiplantibacillus plantarum SCS2 (L. plantarum SCS2) against sodium dextran sulfate (DSS)-induced colitis in mice as well as elucidated its impact on inflammation, oxidative stress, and intestinal microbiota.
View Article and Find Full Text PDFBiogenic Amine-Containing 1,4-Naphthoquinones Mediate Extracellular Electron Transfer in .
Org Lett
September 2025
Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.
, a lactic acid gut bacterium, uses exogenous quinones to facilitate extracellular electron transfer (EET) via type II NADH dehydrogenase (Ndh2). To probe Ndh2 specificity, we designed and evaluated a library of biogenic amine-substituted 1,4-naphthoquinones in an Ndh2-dependent EET assay. Analysis of mediator Ndh2 binding interactions revealed that activity correlates with key binding interactions.
View Article and Find Full Text PDFGEMsembler: consensus model assembly and structural comparison of genome-scale metabolic models across tools improve functional performance.
mSystems
September 2025
Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Genome-scale metabolic models (GEMs) are widely used in systems biology to investigate metabolism and predict perturbation responses. Automatic GEM reconstruction tools generate GEMs with different properties and predictive capacities for the same organism. Since different models can excel at different tasks, combining them can increase metabolic network certainty and enhance model performance.
View Article and Find Full Text PDFGenomic and stress resistance characterization of GX17, a potential probiotic for animal feed applications.
Microbiol Spectr
September 2025
Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning, Guangxi, China.
Unlabelled: Lactobacilli, recognized as beneficial bacteria within the human body, are celebrated for their multifaceted probiotic functions, including the regulation of intestinal flora, enhancement of body immunity, and promotion of nutrient absorption. This study comprehensively analyzed the genotypic and phenotypic characteristics of () strains isolated from the intestines of healthy chicks and assessed their potential as probiotics. The assembled genome consists of 29,521,986 bp, and a total of 1,771 coding sequences (CDSs) were predicted.
View Article and Find Full Text PDFEffects of fermentation with different lactic acid bacteria on the physicochemical, electronic sensory, and aroma profiles of heat-sterilized tomato juice.
Food Sci Biotechnol
October 2025
Engineering Research Center of Storage and Processing of Xinjiang Characteristic Fruits and Vegetables, Ministry of Education, School of Food Science, Shihezi University, Shihezi, 832000 Xinjiang China.
The current work aimed to investigate the effects of fermentation of , , and on the physicochemical, electronic sensory evaluation, and flavour characteristics of heat-sterilized tomato juice (HTJ). The results indicated that LAB fermentation significantly decreased the pH, sucrose, and glucose, and lactic acid was increased. E-nose and tongue analyses revealed that the response to organic sulfides, terpenoids, and sourness increased after LAB fermentation HS-SPME-GC-MS and OAV revealed that heat-sterilization resulted a significant loss of aroma compounds (38.
View Article and Find Full Text PDF