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Background: The present study assessed adherence and satisfaction regarding a new protocol for preventing hypoglycemia in neonates, with a target of 80 % adherence.
Methods: This 6-month prospective observational study was conducted between 2021 and 2022 in a tertiary hospital maternity unit. Neonates with at least one hypoglycemia risk factor were included. Two factors for adherence were evaluated: feeding before 1 h of life and capillary blood glucose assay at 2 h of life.
Results: Protocol adherence was 67.6 % overall, with clinically satisfactory protocol application. Neonates small for gestational age were at the greatest risk of hypoglycemia (34.8 %). Non-adherence mainly concerned early feeding (28.9 %). The rate of hypoglycemia with adherence and non-adherence was, respectively, 15.8 % (n = 27/171) and 22.0 % (n = 18/82) (p = 0.23). Teams integrated the new recommendations successfully (satisfaction: 8/10), with some reluctance on the part of childcare assistants due to increased workload.
Conclusion: This apparently simple protocol could be supported by a quality improvement program. This study might help other care teams to establish similar protocols and identify areas for improvement.
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http://dx.doi.org/10.1016/j.arcped.2024.07.008 | DOI Listing |
Infection
September 2025
Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark.
Purpose: To investigate bacteriology, antibiotic treatment and adverse birth outcomes (ABOs) in pregnancies with and without bacteriuria and urinary tract infections (UTIs) based on urine cultures and clinical diagnoses.
Methods: Registry-based cohort study.
Population: Pregnancies with at least one urine culture analysed at one of two hospitals in the Capital Region, Denmark, between 2015 and 2021.
Mov Disord
September 2025
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Background: Adverse pregnancy and neonatal outcomes in women with Tourette syndrome or chronic tic disorder (TS/CTD) have not been systematically studied. This Swedish population-based study investigated associations between maternal TS/CTD and pregnancy, delivery, and neonatal outcomes.
Methods: We included all singleton births at ≥22 weeks between 2001 and 2021.
Stroke
September 2025
Division of Neonatology, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, the Netherlands. (B.O.v.O., M.R., M.S.S., E.L., L.S.d.V., S.J.S.).
Background: Monochorionic twins, characterized by placental sharing and vascular anastomoses, carry a high risk of brain injury, including perinatal arterial ischemic stroke (PAIS). However, the pathophysiology and timing-related risk factors of PAIS remain unclear.
Methods: Retrospective cohort of all monochorionic twins with neuroimaging-confirmed PAIS born from 2005 to 2024 and evaluated at a Dutch national referral center.
J Oral Microbiol
September 2025
Department of Pediatric Dentistry, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Background: The neonatal period is critical for oral microbiome establishment, but temporal patterns in preterm newborns remain unclear. This study examined longitudinal microbiome changes in full-term and preterm newborns and assessed perinatal and clinical influences.
Methods: Oral swabs were collected from 98 newborns (23 full-term, 75 preterm).
Int J Pediatr
August 2025
Department of Neonatology, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
This study is aimed at evaluating the cumulative effect of postnatal risk factors on the survival of preterm neonates by examining key clinical parameters and complications across various gestational ages. A retrospective cohort study was conducted using data from 1109 neonates admitted to neonatal intensive care units at two tertiary regional hospitals in Kazakhstan between 2021 and 2024. Patients were classified into three groups based on gestational age: extremely preterm (< 28 weeks, = 223), very preterm (28-31 weeks, = 384), and moderate to late preterm (32-36 weeks, = 502).
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