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Background And Objectives: The Transforming Clinical Practices Initiative (TCPI) was a 4-year, large-scale, collaborative, peer-based learning initiative for physician practices of all specialties with broad goals to improve the quality of patient care, spend health care dollars more wisely, and assist practices in being ready to succeed under value-based payment (VBP). We investigated whether the COVID-19 pandemic had erased or diminished practice transformation progress made during the TCPI program period, through a follow-up survey of participating practices fielded in October 2021.
Methods: In October 2021 to April 2022, we surveyed a probability sample of 2207 primary care and specialty practices that participated in the TCPI, receiving 610 responses. We asked about practice characteristics, financial and ownership stability, clinical performance, and quality improvement efforts, both now and prior to COVID-19. The COVID-19 content was part of a larger survey. Responses were weighted to account for sample selection, unknown eligibility status, and nonresponse. We generated weighted univariate descriptive statistics representative of practices with clinicians enrolled in TCPI. These estimated percentages have a 95% confidence interval of about ±5%. Multivariate analysis of unweighted data examined associations between practice characteristics and other variables of interest.
Results: For all but one of 13 practice transformation activities engaged in prior to the COVID-19 public health emergency, a majority of practices (at least 52%) reported that the progress on these activities were either not hurt or were helped by their COVID-19 experience. Compared to January 2020, only about 7% of practices reported that their quality of care or clinical performance was worse due to COVID-19, and 32% reported that their quality of care was better. More rural than urban practices reported that half or more of their transformation activities were hurt by COVID-19 (29% and 14%, respectively). Physician-owned practices were more likely to report quality is better today than prior to COVID-19 relative to practices with other ownership types such as hospitals or health systems (43% vs 24%).
Conclusions: Most practices have been able to recover from the deep stress of the COVID-19 pandemic and continue their efforts to improve patient care and performance to succeed under VBP. These results suggest a high perceived return on investment in value-readiness support along with emergency financial support in times of crisis, as well as room to continue preparation for any future pandemic and the national movement toward increased VBP, especially in rural settings.
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http://dx.doi.org/10.1097/QMH.0000000000000472 | DOI Listing |
J Am Chem Soc
September 2025
National Engineering Research Center of Lower-Carbon Catalysis Technology, Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Zeolite-confined Rh-based catalysts have emerged as promising heterogeneous candidates for olefin hydroformylation. However, they face challenges of reactant- and product-induced Rh leaching and aggregation. Herein, zeolite framework-anchored Rh-(O-Zn) sites were designed and are shown to have remarkable activity and stability for gas-phase ethylene hydroformylation.
View Article and Find Full Text PDFOrg Lett
September 2025
Hubei Key Laboratory of Pollutant Analysis & Reuse Technology, College of Chemistry and Chemical Engineering, Hubei Normal University, Huangshi 435002, P. R. China.
A regioselective C3-H alkynylation of triazolopyridazines has been achieved via dual gold/silver catalysis employing hypervalent iodine(III) reagents. The transformation proceeds through an alkynyl Au(III) intermediate and a silver-assisted C-H activation pathway, delivering a broad range of 3-alkynylated triazolopyridazines in good to excellent yields. Mechanistic studies, including H/D exchange experiments, reveal that the silver species plays a crucial role in facilitating C-H activation.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
September 2025
Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, ON, Canada.
to explore sex and heating rate effects on frequency-domain indicators of the mechanisms modulating cutaneous vasodilation during local heating. In thirty young adults (21±3 years, 15 females), wavelet analysis of skin blood flux was assessed from laser-Doppler flux signals at the chest, abdomen, arm, forearm, thigh, and calf during rapid (33-42°C; 1°C·20 s) and gradual (33-42°C; 1°C·5 min) local skin heating. A wavelet transform using a Morlet mother wavelet was computed over the entire signal for each heating protocol (minimum 90 minutes) and 5-min time windows were subsequently isolated to determine responses during baseline and the 42°C heating plateau.
View Article and Find Full Text PDFOrg Lett
September 2025
College of Materials and Chemical Engineering, Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, China Three Gorges University, Yichang, Hubei 443002, P. R. China.
A novel copper-catalyzed radical cross-coupling reaction for the thioesterification of polyfluoroarenes is developed using KS and aldehydes in water. This protocol employs a readily available KS as a sulfur source, eliminating the need for hazardous thiols and organic solvents. The mild reaction conditions are compatible with a wide range of functional groups, providing access to diverse polyfluoroaryl thioesters.
View Article and Find Full Text PDFQual Life Res
September 2025
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, 250012, Shandong, China.
Purpose: The study aimed to assess the interconnection of quality of life (QoL) variables and identify key areas for which interventions could improve QoL among men who have sex with men (MSM) living with HIV on antiretroviral therapy (ART).
Methods: A cross-sectional study was conducted in Jinan of Shandong Province, between October to December 2020. Undirected network analyses were conducted to examine and visualize the interconnections between QoL variables among MSM living with HIV.