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The aim of this prospective study was to investigate the effect of a first and repeated complex decongestive therapy (CDT) program on volume and functioning in patients with unilateral breast cancer-related lymphedema (BCRL) and to identify whether the volume before treatment and/or the number of previous treatment influence outcomes. In total, 100 and 42 patients with BCRL treated by 499 CDT (6 hours a day during 5 consecutive days) between April 2018 and December 2021 were included. Patients were assessed using volume including percentage of excess volume and percentage reduction in excess volume and lymph-International Classification of Functioning-UL questionnaire. After CDT, a significant reduction in BCRL volume (50%) and improvement in functioning (30%) were observed. The volume reduction was greater when the BCRL volume before treatment was low (10%-20%) and when CDT was performed for the first time. The functioning improvement was identical whatever the volume is before treatment and the number of previous CDT. A greater volume reduction after CDT was obtained in BCRL with low volume before treatment and after the first CDT. Such findings support the need for early intensive BCRL treatment to control volume and improve functioning.
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http://dx.doi.org/10.1089/lrb.2024.0013 | DOI Listing |
Jpn J Ophthalmol
September 2025
Kyorin Eye Center, School of Medicine, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Purpose: To evaluate the clinical outcomes of pneumatic retinopexy (PnR) for a recurrent rhegmatogenous retinal detachment (RRD) due to superior retinal breaks following initial vitrectomy for a RRD.
Study Design: Clinical investigations.
Methods: A retrospective study of 82 eyes of 82 patients who underwent vitrectomy by a single surgeon between November 2021 and March 2023.
Langmuir
September 2025
Centre for Biomedical Engineering, Indian Institute of Technology, Delhi, New Delhi 110016, India.
The study addresses the critical issue of sepsis diagnosis, a life-threatening condition triggered by the body's immune response to infection that leads to mortality. Current diagnostic methods rely on the time-consuming assessment of multiple biomarkers by a series of tests, leading to delayed treatment. Here, we report a platform for developing a point-of-care (POC) device utilizing electrochemical immunosensors for the dual and rapid detection of sepsis biomarkers: Procalcitonin (PCT), Interleukin-6 (IL-6), and C-reactive protein (CRP) as host markers and lipopolysaccharide (LPS) as a pathogen marker.
View Article and Find Full Text PDFNeuroradiology
September 2025
Department of Diagnostic and Interventional Neuroradiology, Klinikum Solingen, Solingen, Germany.
Purpose: This study aims to evaluate the safety and efficacy of the CGuard dual-layer stent with its mesh embolic protection system (EPS) in elective cases for treatment of internal carotid artery stenosis and compares it to the Carotid Wallstent as benchmark.
Methods: In this retrospective, multicenter study, we analyzed data from consecutive patients who underwent carotid artery stenting with CGuard at two high-volume neurointerventional centers and compared them with prior consecutive patients treated with Carotid Wallstent (CWS), with and without a balloon guiding catheter (BGC) as protection, at the same institutions. Patient demographics, procedural details, clinical complications, early in-stent thrombosis and occlusion rates, and late follow-up restenosis rates were assessed.
Interv Neuroradiol
September 2025
J.J. Merland Department of Therapeutic Neuroangiography, University General Hospital of Catalonia and Hospital del Mar, Barcelona, Spain.
Background and purposeThis study presents our initial experience using Obtura, a novel nonadhesive liquid embolic agent with extra-low viscosity variants, in transvenous curative embolization of brain arteriovenous malformations (bAVMs). We assess the agent's performance and compare its advantages with other extra-low viscosity options currently available.Materials and methodsFive patients (three females, two males; mean age, 33 years; range, 20-55 years) with ruptured bAVMs were treated using the transvenous retrograde pressure cooker technique (TVRPCT).
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objectives: To provide a bibliometric overview of the global research on the therapeutic applications of the suprachoroidal space (SCS) from 2000 to 2024.
Methods: Publications were retrieved from the Web of Science Core Collection using a defined search strategy. A total of 776 articles were analyzed for trends in publication volume, countries, institutions, authorship, journals, citations, and keywords.