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Background: Spaced digital education applies digital tools to deliver educational content via multiple, repeated learning sessions separated by prespecified time intervals. Spaced digital education appears to promote acquisition and long-term retention of knowledge, skills, and change in clinical behavior.
Objective: The aim of this review was to assess the effectiveness of spaced digital education in improving pre- and postregistration health care professionals' knowledge, skills, attitudes, satisfaction, and change in clinical behavior.
Methods: This review followed Cochrane's methodology and PRISMA (Preferred Reporting Items of Systematic Reviews and Meta-Analyses) reporting guidelines. We searched MEDLINE, Embase, Web of Science, ERIC, PsycINFO, CINAHL, CENTRAL, and ProQuest Dissertation and Theses databases from January 1990 to February 2023. We included randomized controlled trials (RCTs), cluster RCTs, and quasi-RCTs comparing spaced digital education with nonspaced education, spaced nondigital education, traditional learning, or no intervention for pre- or postregistration health care professionals. Study selection, data extraction, study quality, and certainty of evidence were assessed by 2 independent reviewers. Meta-analyses were conducted using random effect models.
Results: We included 23 studies evaluating spaced online education (n=17, 74%) or spaced digital simulation (n=6, 26%) interventions. Most studies assessed 1 or 2 outcomes, including knowledge (n=15, 65%), skills (n=9, 39%), attitudes (n=8, 35%), clinical behavior change (n=8, 35%), and satisfaction (n=7, 30%). Most studies had an unclear or a high risk of bias (n=19, 83%). Spaced online education was superior to massed online education for postintervention knowledge (n=9, 39%; standardized mean difference [SMD] 0.32, 95% CI 0.13-0.51, I=66%, moderate certainty of evidence). Spaced online education (n=3, 13%) was superior to massed online education (n=2, 9%) and no intervention (n=1, 4%; SMD 0.67, 95% CI 0.43-0.91, I=5%, moderate certainty of evidence) for postintervention clinical behavior change. Spaced digital simulation was superior to massed simulation for postintervention surgical skills (n=2, 9%; SMD 1.15, 95% CI 0.34-1.96, I=74%, low certainty of evidence). Spaced digital education positively impacted confidence and satisfaction with the intervention.
Conclusions: Spaced digital education is effective in improving knowledge, particularly in substantially improving surgical skills and promoting clinical behavior change in pre- and postregistration health care professionals. Our findings support the use of spaced digital education interventions in undergraduate and postgraduate health profession education. Trial Registration: PROSPERO CRD42021241969.
Trial Registration: PROSPERO CRD42021241969; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=241969.
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http://dx.doi.org/10.2196/57760 | DOI Listing |
J Oral Maxillofac Surg
September 2025
Associate Professor, Department of Oral and Maxillofacial Surgery, University of Tennessee Medical Center in Knoxville, Knoxville, TN.
Nanoscale
August 2025
Centre for Theoretical Physics and Natural Philosophy, Nakhonsawan Studiorum for Advanced Studies, Mahidol University, Nakhonsawan, 60130, Thailand.
The exponential growth of the global population in the digital era has accelerated urbanization and industrialization, leading to severe complex water pollution from the discharge of toxic dyes into aquatic ecosystems. Two dimensional (2D) MXene-based nano-adsorbents recently emerged as promising candidates for developing sustainable wastewater remediation technologies due to their tunable physicochemical properties, including a high negative zeta potential, a large specific surface area, exceptional adsorption capacity, superior electrical and thermal conductivity, hydrophilicity, and rich surface chemistry. Strategic optimization approaches for MXenes, encompassing interlayer spacing modification, surface engineering, stoichiometric tuning, morphological control, bandgap engineering, membrane fabrication, hybridization, and functionalization, have significantly enhanced their adsorptive performance and dye removal efficiency for real-time wastewater treatment applications.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Orthodontics, School of Dentistry, Kanagawa Dental University, Yokosuka 238-8580, Japan.
Paired box gene 3 () plays an important role in craniofacial development. Mutations in this gene are associated with Waardenburg syndrome, which is a condition characterized by facial anomalies such as widely spaced inner corners of the eyes. gene polymorphisms are associated with the relative position of the nasal root (nasion), even among healthy individuals.
View Article and Find Full Text PDFJ Neurosurg
August 2025
Departments of1Neurosurgery and.
Objective: Carotid artery atherosclerotic plaques undergo various pathological changes during disease progression, and their characterization relies on MRI, CT, and ultrasound imaging. The diagnosis of calcified lesions using only MRI is challenging because of irregular low-signal areas across all sequences. Conventionally, a diagnosis is made by combining multiple modalities such as contrast-enhanced CT (CECT) and carotid ultrasonography.
View Article and Find Full Text PDFEur J Prosthodont Restor Dent
August 2025
Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Objectives: Conflicting evidence exists regarding the optimal impression thickness and the influence of tray spacing on the accuracy of elastomeric impressions and resulting casts. This study evaluated the effect of three tray spacings (2 mm, 4 mm, and 6 mm) on the dimensional accuracy of three addition silicone impression materials (Aquasil, Panasil, and Elite-HD).
Methods: Forty-five impressions of a partially dentate maxillary resin cast were made using standardized custom trays with designated spacer thicknesses.