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Article Abstract
Introduction: Trimethylamine N-oxide (TMAO) is a gut bacteria-dependent metabolite associated with poor cardiovascular health. Exercise is a known cardioprotective activity but the impact of an acute bout of exercise on TMAO production is unknown.
Objectives/methods: This study assessed choline-derived production of TMAO following a single bout of intermittent exercise in a young, healthy cohort.
Results: Choline supplemented after either exercise or a time-matched resting period demonstrated a similar increase in circulating TMAO across an 8-hour period.
Conclusion: This suggests that a single bout of intermittent exercise does not alter gut microbial metabolic behaviour and thus does not provide additional cardioprotective benefits related to blood levels of TMAO.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11455687 | PMC |
| http://dx.doi.org/10.1007/s11306-024-02177-0 | DOI Listing |
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