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The role of genomic research and medicine in improving health continues to grow significantly, highlighting the need for increased equitable inclusion of diverse populations in genomics. Native Hawaiian and Pacific Islander (NHPI) communities are often missing from these efforts to ensure that the benefits of genomics are accessible to all individuals. In this article, we analyze the qualities of NHPI populations relevant to their inclusion in genomic research and investigate their current representation using data from the genome-wide association studies (GWAS) catalog. A discussion of the barriers NHPI experience regarding participating in research and recommendations to improve NHPI representation in genomic research are also included.
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http://dx.doi.org/10.1038/s41525-024-00428-6 | DOI Listing |
Am J Public Health
October 2025
Joseph Keawe'aimoku Kaholokula is a professor and chair of Native Hawaiian Health at the John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu.
JMIR Hum Factors
September 2025
Department of Community Health Systems, University of California, San Francisco, School of Nursing, San Francisco, CA, United States.
Background: The COVID-19 pandemic forced the world to quarantine to slow the rate of transmission, causing communities to transition into virtual spaces. Asian American and Pacific Islander communities faced the additional challenge of discrimination that stemmed from racist and xenophobic rhetoric in the media. Limited data exist on technology use among Asian American and Pacific Islander adults during the height of the COVID-19 shelter-in-place period and its effect on their physical and mental health.
View Article and Find Full Text PDFNeurology
October 2025
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Objectives: Status epilepticus (SE) is a life-threatening neurologic emergency. Although health disparities in epilepsy are well-documented, disparities in SE mortality are not fully understood. This study analyzes mortality trends and demographics in the United States from 1999 through 2020.
View Article and Find Full Text PDFJAMIA Open
October 2025
Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.
Objectives: Type 2 diabetes (T2D) is a growing public health burden with persistent racial and ethnic disparities. . This study assessed the completeness of social determinants of health (SdoH) data for patients with T2D in Epic Cosmos, a nationwide, cross-institutional electronic health recors (EHR) database.
View Article and Find Full Text PDFGlob Adv Integr Med Health
September 2025
Native Hawaiian and Indigenous Health, Department of Public Health Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Background: Integrative health efforts typically offer clinical services of Western and non-Western origin in a biomedical context. Indigenous communities and other minoritized populations would benefit from improved equity efforts in integrative healthcare.
Objective: As an approach to improve healthcare for Kānaka 'Ōiwi (Native Hawaiians), we explore multi-eyed seeing, an elaboration on two-eyed seeing, emphasizing decolonialism and adaptive use of healing traditions from multiple cultural backgrounds.