Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Pasteurella spp. can cause fatal zoonotic infections in humans. We performed a multicenter study to investigate the prevalence and clinical features of Pasteurella infections in South Korea during 2018‒2022. We also conducted a collaborative systematic review and meta-analysis of the global burden of Pasteurella bacteremia. The study included 283 cases found an increasing trend in Pasteurella infections. Blood cultures were positive in 8/35 (22.9%) cases sampled, for overall bacteremia-associated rate of 2.8% (8/283). Aging was a significant risk factor for bacteremia (odds ratio 1.05 [95% CI 1.01-1.10]), according to multivariate analyses. For the meta-analysis, we included a total of 2,012 cases from 10 studies. The pooled prevalence of bacteremia was 12.4% (95% CI 7.3%-18.6%) and of mortality 8.4% (95% CI 2.7%-16.5%). Our findings reflect the need for greater understanding of the increase in Pasteurella infections and the global burden of Pasteurella bacteremia to determine appropriate case management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11431893PMC
http://dx.doi.org/10.3201/eid3010.240245DOI Listing

Publication Analysis

Top Keywords

pasteurella infections
16
pasteurella bacteremia
12
pasteurella
8
infections south
8
south korea
8
systematic review
8
review meta-analysis
8
global burden
8
burden pasteurella
8
bacteremia
5

Similar Publications

Infections resulting from wild land and aquatic species injuries: A case series from Mornington Peninsula, Australia.

Injury

August 2025

Monash University, Faculty of Medicine, Nursing and Health Sciences, Monash, Victoria 3800, Australia; Department of Plastic and Reconstructive Surgery, Peninsula Health, Melbourne, Victoria 3199, Australia.

Background: Urban expansion into natural habitats has increased human interactions with wild terrestrial and aquatic species, leading to a rise in animal-related injuries. These incidents often result in complex infections, posing major public health challenges. This study examines the epidemiology, therapeutic interventions, and clinical outcomes of infections from non-domesticated animal injuries in the Mornington Peninsula, Australia.

View Article and Find Full Text PDF

() is a zoonotic pathogen that poses a significant threat to animal health and causes substantial economic losses, further aggravated by rising tetracycline resistance. To restore the efficacy of tetracyclines to , we evaluated the synergistic antibacterial activity of doxycycline combined with metformin, an FDA-approved antidiabetic agent. Among several non-antibiotic adjuvant candidates, metformin exhibited the most potent in vitro synergy with doxycycline, especially against capsular serogroup A strain (A).

View Article and Find Full Text PDF

Cat bites frequently lead to polymicrobial infections due to deep puncture wounds that inoculate oral flora into poorly oxygenated tissues. While is the most commonly implicated organism, environmental and atypical pathogens may also play a role, yet often go unrecognized. This article reports a rare case of polymicrobial septic arthritis caused by a domestic cat bite in an immunocompetent adult, with isolation of , a freshwater-associated species not previously reported in this context.

View Article and Find Full Text PDF

Calreticulin in the nasal mucus promotes neutrophil migration and pathogen clearance.

Cell Commun Signal

August 2025

MOE Joint International Research Laboratory of Animal Health and Food Safety, college of veterinary medicine, Nanjing Agricultural University, Weigang 1, Nanjing, Jiangsu, 210095, PR China.

The nasal cavity harbors diverse microbiota, and the nasal mucosal innate defense against microbial infiltration is crucial for respiratory infections. Both the nasal mucus covering the surface of the nasal cavity and the neutrophils beneath the nasal epithelia are the first line of innate defense against pathogens. Studying nasal mucus is challenging because of difficulties in collecting stable, high-quality samples from humans.

View Article and Find Full Text PDF

Pasteurella multocida has a high genotypic variability, which allows it to cause a wide variety of diseases with huge economic losses worldwide. In this study, whole genome sequencing (WGS) of 66 P. multocida strains isolated from different host species was performed.

View Article and Find Full Text PDF