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Excessive use of insecticides are responsible to contaminate the environment, soil health, developing resistance in the insect pests, introduces new species, toxic to human and eliminates non-target organisms and affects the eco-balance and biodiversity adversely. Application of microbial bio-agents with the chemical insecticides is an assertive way to manage the population of pests, in an addition to dropping down the chemical residues risk to the eco-system. Larval stages of are prolific eater, caused huge losses globally. Individual and combined effect of chemical insecticides Barazide (Novaluron 5.25 %+Emamectin benzoate 0.9 % SC), entomopathogenic bacterial ( var. ), and entomopathogenic fungus ( and ) is assessed against the larvae of in bio-assay experiment. The decreasing trend in the observed mortality among insecticides alone is Barazide (95.80 ± 1.16, 85.30 ± 1.85 and 82.00 ± 1.72) > var. (88.70 ± 1.01, 79.90 ± 2.01 and 78.00 ± 2.91) > (82.60 ± 2.46, 73.90 ± 2.46 and 73.00 ± 4.16) > (78.60 ± 1.46, 68.90 ± 2.96 and 69.00 ± 3.46) after 96 h at its highest inoculation level against 3rd, 4th and 5th instar larvae. The combined application of Barazide @0.1 % with @1.5%induced mortality cent percent after 72 and 96 h against 3rd and 4th instar. Chi-squared test indicated a significant level of mortality at p < 0.05 level at highest dose and the probit analysis showed lowest LC value at dose 5.15 and 7.63 % with 95 % FL:1.38-19.22 and 2.85-20.39 after 72 and 96 h of exposure against 3rd and 4th instar. The increasing trend in the observed mortality among insecticides used in combination is Barazide + < Barazide + < Barazide + . Insecticides used in combination induced synergism that providing valuable practice to manage insect pests. These results suggested that the combined treatments could be a successful method for controlling the population of and at the same time farmers will decrease the inappropriate misuse and overuse of harmful chemical insecticides.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11408058 | PMC |
http://dx.doi.org/10.1016/j.heliyon.2024.e37175 | DOI Listing |
Pestic Biochem Physiol
November 2025
Anhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, School of Resource & Environment, Anhui Agricultural University, Hefei, Anhui 230036, China; Institute of Ecological Environmental Protection and Pollution Remediation Engineering, Anhui Agricultural U
Neonicotinoid insecticides residuals pose a threat to aquatic ecosystems and human health. Imidaclothiz, as a novel neonicotinoid pesticide, the metabolic mechanisms in aquatic environments was unclear. This study investigated the degradation characteristics of imidaclothiz in both pure and actual water, and analyzed the photodegradation and hydrolysis metabolites of imidaclothiz in aquatic environments and assessed their toxicity.
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November 2025
Marine College, Shandong University, Weihai, Shandong 264209, China. Electronic address:
Tralopyril (TP), a representative bromopyrrolonitrile, functions as a broad-spectrum insecticide, raising growing concerns about its potential impact on aquatic organisms and human intestinal health. However, the key targets and toxicity mechanisms underlying TP-induced enteritis remain unclear. In this study, we utilized network toxicology combined with molecular docking to comprehensively explore the potential molecular mechanisms underlying TP-induced enteritis.
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November 2025
Henan Engineering Laboratory of Pest Biological Control/College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, People's Republic of China.
Henosepilachna vigintioctopunctata represents a significant economic pest, typically controlled through the use of chemical insecticides. The introduction of RNA interference (RNAi) technology has opened new avenues for biopesticide development, leading to the identification of various genes that are crucial for the growth and development of insects. However, the efficient screening of target genes in H.
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November 2025
Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China; Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural
The olfactory system of insects plays a vital role in their survival by enabling them to detect chemical cues and adapt to changing environments. The rape stem weevil, Ceutorhynchus asper, is a significant pest posing a challenge for rapeseed production due to its destructive feeding habit and increasing resistance to insecticides. So far, there's still limited knowledge about structure and function of odorant binding proteins (OBPs) in beetles like C.
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November 2025
Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, Key Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, School of Life Sciences, China Jiliang University, Hangzhou 310018, China. Electronic a
The brown planthopper (BPH) Nilaparvata lugens is one of the most destructive pests of rice, and its management has primarily relied on chemical insecticides. Currently, the chemical management of BPH is facing challenges due to the development of pesticide resistance. RNA interference (RNAi) provides attractive alternative to chemical insecticides, provided that suitable target genes are identified.
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