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Tailgut cysts are rare lesions which are found in the rectorectal space. They develop in the final section of the intestine from which the rectum and anus extend and vary from being asymptomatic to symptomatic due to pressure on organs or nerves. Tailgut cysts are more common in females, usually between 30 and 60 years of age. They are thought to be benign, with variable malignancy risks. Surgical excision followed by histological examination is the gold standard of treatment, but access and approach to tailgut cysts depend on the location and morphology of the lesion. We present two symptomatic cases of this very rare pathology. In both cases, the cyst and coccyx bone were successfully excised using different approaches. The first patient was a 40-year-old woman with a large cyst which caused morning tenesmus, urinary outflow disorders and painful ovulation. Due to the cyst size, laparotomy was performed, and a combined approach was used. The second patient is a 36-year-old woman with co-existing endometriosis and a cyst causing pain in the sacral spine, constipation and tenesmus. The tumor was excised using a Kraske approach, and due to the infiltration of the coccyx bone it was removed using an osteotome. In this patient, perforation of the cyst was also observed. Both patients completed follow-ups involving regular surgical check-ups and MRI scans. Descriptions of different symptoms and surgical approaches make our study an important source of knowledge for diagnosing and treating these very rare tumors.
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http://dx.doi.org/10.3390/jcm13175136 | DOI Listing |
J Gastrointest Surg
July 2025
Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, United States.
Int J Surg Case Rep
September 2025
Gastrointestinal Oncology Unit, Acibadem University Atakent Hospital, Istanbul, Turkey. Electronic address:
Introduction And Importance: Tailgut cysts (TGC) are rare retrorectal lesions originating from embryological remnants of the hindgut. Malignant transition is rare; treating it with an unplanned diagnostic algorithm can complicate the clinical course.
Case Presentation: We report a case of retrorectal mucinous adenocarcinoma arising from a TGC in a 63-year-old female.
Radiol Case Rep
August 2025
College of Medicine, Hebron University, Hebron, West Bank, Palestine.
Tailgut cysts (TGCs) are rare congenital lesions arising from incomplete regression of the embryonic hindgut, typically located in the presacral space and more common in females. Although often benign, these cysts carry a risk of malignant transformation. We report a case of a woman in her early 50s who presented with abdominal pain, urinary retention, and tenesmus.
View Article and Find Full Text PDFAnn Med Surg (Lond)
January 2025
Department of Medicine, Tentishev Satkynbai Memorial Asian Medical Institute, Gagarina, Kant, Kyrgyzstan.
Introduction: Tailgut cysts, or retro-rectal cystic hamartomas, are rare congenital lesions arising from embryonic hindgut remnants, typically located in the retro-rectal area. These cysts present some diagnostic challenges due to vague symptoms and potential for malignancy.
Case Presentation: A 25-year-old female presented with a 5-year history of perianal swelling.
BMJ Case Rep
March 2025
General Surgery, San Antonio Military Medical Center, Fort Sam Houston, Texas, USA.
Retrorectal tailgut cysts are rare congenital cystic lesions that are found in the presacral space. A case of a woman in her 50s who had an incidental finding of a 7 cm presacral mass after an initial chief concern of flank pain is presented in this report. Further work-up with MRI and colonoscopy demonstrated an extraluminal cystic mass within the retrorectal space with hyperintense foci on T1-weighted imaging.
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