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Left ventricular thrombus (LVT) is a severe consequence that typically follows acute myocardial infarction (MI) and can occur in nonischemic cardiomyopathies. In patients who have experienced an ST-segment elevation acute myocardial infarction (STEMI), LVT is seen up to 15% of the time; for patients without an ischemic cardiomyopathy, it is only 2% to 36% of the time. According to Virchow's triad, the cornerstone of LVT formation includes endothelial injury, blood stasis, and hypercoagulability. However, LVT increases morbidity and mortality in patients with both ischemic and nonischemic cardiomyopathies by increasing the risk of stroke or systemic embolism. Studies on nonischemic etiology are limited, and the majority of LVT case series concentrate on ischemic cardiomyopathies. We present this case with the nonischemic cardiomyopathies caused by LVT. Specifically, the patient underwent coronary artery assessment using photon-counting computed tomography, which is among the most advanced systems worldwide.
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http://dx.doi.org/10.1016/j.radcr.2024.07.179 | DOI Listing |
Cardiovasc Hematol Agents Med Chem
September 2025
Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Background: Pulmonary Hypertension (PH) is a significant contributor to cardiac mortality in Dilated Cardiomyopathy (DCM) patients. Inflammatory processes and oxidative stress play pivotal roles in the advancement of Pulmonary Hypertension (PH). The Monocyte-to-High-- Density-Lipoprotein Cholesterol Ratio (MHR), a newly identified biomarker indicative of inflammatory and oxidative stress, has not been extensively researched in the context of pulmonary hypertension, especially within the scope of dilated cardiomyopathy.
View Article and Find Full Text PDFInt J Cardiovasc Imaging
September 2025
Heart & Vascular Institute, Henry Ford Hospital Detroit, Henry Ford West Bloomfield Hospital 5, West Bloomfield, MI, USA.
Transthoracic echocardiography (TTE) at the time of acute decompensated heart failure (ADHF) may reveal significant structural and hemodynamic abnormalities that can guide clinical management. However, the impact of routine repeat TTE in uncomplicated ADHF re-admissions is yet to be established. We studied patients with repeat TTE at the time of rehospitalization for ADHF to determine downstream clinical impact.
View Article and Find Full Text PDFJ Investig Med High Impact Case Rep
September 2025
Department of Cardiology, St Joseph's University Medical Center, Paterson, NJ, USA.
Wellens' syndrome is characterized by a distinct electrocardiographic pattern, most notably biphasic or deeply inverted T waves in the anterior precordial leads, particularly V2 and V3. These findings typically reflect transient myocardial ischemia resulting from critical stenosis of the proximal left anterior descending (LAD) artery. They are often a warning sign of an impending anterior wall myocardial infarction.
View Article and Find Full Text PDFInsights Imaging
August 2025
Department of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Objectives: This study aimed to assess the feasibility of left ventricular myocardial characterization in patients with ventricular arrhythmias using late enhancement (LE) photon-counting detector computed tomography (PCD-CT) scans, in comparison with invasive endocardial electroanatomical mapping (EAM).
Materials And Methods: This single-center retrospective observational study included 20 patients (mean age 64 ± 8 years, 4 female) who underwent PCD-CT prior to 3D endocardial uni- and bipolar EAM and radiofrequency catheter ablation (RFCA) between May 2022 and February 2024. Sixteen patients (80%) had cardiac implantable electronic devices.
Insights Imaging
August 2025
Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases of China, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objectives: To assess the left ventricular remodeling index (LVRI) for predicting ventricular tachyarrhythmia (VTA) in patients with dilated cardiomyopathy (DCM) with left ventricular ejection fraction (LVEF) < 35%.
Materials And Methods: In this retrospective single-center study, consecutive DCM patients with LVEF < 35% (n = 271) who underwent cardiac magnetic resonance (CMR) imaging were followed up. The study endpoint was VTA, including sudden cardiac death and major ventricular arrhythmias.