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Carbon quantum dots (CQDs) are ideal fluorescent probes for rapid detection. This paper reviews the synthesis methods of CQDs, their application in the rapid detection of antibiotics and heavy metals in the environment and food, and the underlying detection mechanisms. The hydrothermal method is the most commonly used for synthesis, and CQDs doped with heteroatoms (such as N, P and S) exhibit superior fluorescence performance. In the presence of antibiotics and heavy metals, the fluorescence of CQDs can be quenched or enhanced. Single-signal and dual-signal probes can be developed using the fluorescence, phosphorescence and absorbance of CQDs, enabling rapid detection of various antibiotics (e.g., tetracycline, quinolone and beta-lactam antibiotics) and heavy metals (e.g., Cd, Cr, Fe, Hg, and Pb). With the combination of smartphones and fluorescent probe test strips developed based on CQDs, on-the-spot rapid detection can be realized. This review offers new insights into the rapid detection of CQDs.
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http://dx.doi.org/10.1016/j.foodchem.2024.141122 | DOI Listing |
ACS Sens
September 2025
METU MEMS Center, Ankara 06530, Türkiye.
Cardiovascular diseases (CVDs) remain a leading cause of death, particularly in developing countries, where their incidence continues to rise. Traditional CVD diagnostic methods are often time-consuming and inconvenient, necessitating more efficient alternatives. Rapid and accurate measurement of cardiac biomarkers released into body fluids is critical for early detection, timely intervention, and improved patient outcomes.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
Institute for Medical Laboratory Diagnostics, Helios University Hospital, Witten/Herdecke University, Wuppertal, Germany.
Carbapenem-resistant organisms (CRO) have rapidly spread worldwide in recent years, posing a significant challenge to both human health and healthcare systems. Timely and accurate detection of CRO, especially carbapenemase-producing and non-fermenters, is crucial for clinical prevention and treatment of these infections. In the present study, we subjected more than 114 multidrug-resistant Gram-negative and non-fermenters to two tests for the timely detection of carbapenemases.
View Article and Find Full Text PDFAJR Am J Roentgenol
September 2025
Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Patients with inflammation-associated coronary artery disease (CAD) may exhibit rapid progression and require regular coronary imaging. To evaluate the diagnostic performance of spectral photon-counting detector (PCD) coronary CTA with reduced radiation and contrast media doses for detecting coronary stenosis and in-stent restenosis in patients with inflammation-associated CAD. This prospective study enrolled patients with inflammation-associated CAD from January 2023 to March 2024.
View Article and Find Full Text PDFSmall
September 2025
Jožef Stefan Institute, Jamova cesta 39, Ljubljana, SI-1000, Slovenia.
The demand for rapid, field-deployable detection of hazardous substances has intensified the search for plasmonic sensors with both high sensitivity and fabrication simplicity. Conventional approaches to plasmonic substrates, however, often rely on lithographic precision or complex chemistries limiting scalability and reproducibility. Here, a facile, one-step synthesis of vertically aligned 2D nanosheets composed of intergrown CuO/CuO crystallites is presented, fabricated via oxygen plasma discharge on copper substrates.
View Article and Find Full Text PDFAnal Chem
September 2025
Department of Laboratory Medicine, Fujian Medical University, Fuzhou 350004, China.
Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in children. Current clinical diagnosis primarily relies on invasive detection methods, while molecular subtyping remains a complex and time-consuming process. This study innovatively employed silver nanoparticle-based surface-enhanced Raman spectroscopy (SERS) technology to systematically analyze 116 serum samples, including those with breakpoint cluster region-Abelson (-) fusion genotype, mixed-lineage leukemia (, also known as lysine methyltransferase 2A, ) gene rearrangement subtype, T-lymphoblastic ALL, and healthy controls.
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