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Background: Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) represents a significant clinical challenge due to its unpredictability and potentially severe outcomes. The Rockall risk score has emerged as a critical tool for prognostic assessment in patients with ANVUGIB, aiding in the prediction of rebleeding and mortality. However, its applicability and accuracy in the Chinese population remain understudied.
Aim: To assess the prognostic value of the Rockall risk score in a Chinese cohort of patients with ANVUGIB.
Methods: A retrospective analysis of 168 ANVUGIB patients' medical records was conducted. The study employed statistical tests, including the -test, test, spearman correlation, and receiver operating characteristic (ROC) analysis, to assess the relationship between the Rockall score and clinical outcomes, specifically focusing on rebleeding events within 3 months post-assessment.
Results: Significant associations were found between the Rockall score and various clinical outcomes. High Rockall scores were significantly associated with rebleeding events ( = 0.735, = 0.541, < 0.001) and strongly positively correlated with adverse outcomes. Low hemoglobin levels ( = 2.843, = 0.005), high international normalized ratio ( = 3.710, < 0.001), active bleeding during endoscopy ( = 7.950, = 0.005), large ulcer size ( = 6.348, < 0.001), and requiring blood transfusion ( = 6.381, = 0.012) were all significantly associated with rebleeding events. Furthermore, differences in treatment and management strategies were identified between patients with and without rebleeding events. ROC analysis indicated the excellent discriminative power (sensitivity: 0.914; specificity: 0.816; area under the curve: 0.933; Youden index: 0.730) of the Rockall score in predicting rebleeding events within 3 months.
Conclusion: This study provides valuable insights into the prognostic value of the Rockall risk score for ANVUGIB in the Chinese population. The results underscore the potential of the Rockall score as an effective tool for risk stratification and prognostication, with implications for guiding risk-appropriate management strategies and optimizing care for patients with ANVUGIB.
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http://dx.doi.org/10.4240/wjgs.v16.i8.2620 | DOI Listing |
J Korean Neurosurg Soc
September 2025
Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Objective: To identify the ideal timing for resuming oral or injectable anticoagulants therapy after spontaneous intracranial hemorrhage (sICH).
Methods: We conducted a retrospective cohort study involving 90 patients from a tertiary hospital in Korea, between June 2000 and May 2022, who had experienced sICH while receiving anticoagulant therapy and who resumed treatment within six months. Exclusions were made for trauma-induced hemorrhages and early post-ictus fatalities.
J Vasc Interv Radiol
August 2025
Department of Radiology, Okinawa Prefectural Chubu Hospital, Okinawa, Japan. Electronic address:
Purpose: To evaluate transarterial embolization (TAE) outcomes in patients with diverticular bleeding confirmed by contrast-enhanced computed tomography (CECT), and to explore factors associated with rebleeding.
Materials And Methods: This retrospective, single-center study included patients with colonic diverticular bleeding who showed active bleeding on CECT and underwent angiography between January 2008 and March 2021. Data included demographics, embolization details, and clinical outcomes.
Endosc Int Open
July 2025
Dept. of Medical Gastroenterology, Asian Institute of Gastroenterology (AIG Hospitals), Hyderabad, India.
Background And Study Aims: Endoscopic spray therapy has been shown to be effective and safe in managing upper gastrointestinal bleeding (UGIB). We aimed to evaluate safety and efficacy of the novel powder-based Resolv Endoscopic Hemostat System in managing UGIB.
Patients And Methods: This was a single-center, prospective, single-arm study conducted from July 2022 to February 2023.
BMC Gastroenterol
August 2025
Department of Surgery, Sakai City Medical Center, 1-1-1 Ebaraji-Cho, Nishi-Ku, Sakai City, Osaka, Japan.
Background: Advanced gastric cancer frequently leads to severe complications, such as bleeding, which severely impacts patients' quality of life and prognosis. Traditional approaches for hemostasis include endoscopic treatments and surgery, but their invasive nature and potential for significant morbidity have made less invasive options like radiation therapy (RT) and transarterial embolization (TAE) appealing. Nonetheless, studies comparing the therapeutic effects and prognosis of RT and TAE are limited, underscoring a significant gap in research and clinical practice.
View Article and Find Full Text PDFJ Neurointerv Surg
August 2025
Neurosurgical Department, Tri-Service General Hospital, Taipei City, Taiwan.
Background: Blood blister-like aneurysms (BBAs) of the internal carotid artery are rare but high risk lesions that frequently re-rupture due to their fragile structure and dissecting pathology. Treatment is particularly challenging in ruptured cases, given the risks associated with dual antiplatelet therapy. Recent advancements in flow diverter stents (FDSs) with surface modifications, and the use of single antiplatelet therapy (SAPT), offer a potential alternative strategy.
View Article and Find Full Text PDF