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http://dx.doi.org/10.1111/1754-9485.13750 | DOI Listing |
PLoS One
September 2025
Center of Emergency Medicine, University Hospital Essen, Essen, Germany.
Background: Survival of out-of-hospital cardiac arrest (OHCA) remains poor even when bystander cardiopulmonary resuscitation (CPR) with chest compression is initiated. Chest compressions provide only reduced cardiac output with limited perfusion of heart and brain and therfore may not avoid both death or poor neurological outcome in prolonged CPR. We investigated the impact of resuscitative endovascular balloon occlusion of the aorta (REBOA) on hemodynamics, gas exchange and return of spontanous circulation (ROSC) with short-term survival during mechanical CPR (mCPR) with chest compression synchronized-ventilation (CCSV) in an atraumatic pig model.
View Article and Find Full Text PDFClostridial myositis and myonecrosis, or gas gangrene, is an acute, rapidly progressive, non-pyogenic, invasive clostridial infection of the muscle tissue characterized by profound toxemia, extensive edema, massive death of tissue, and a variable degree of gas production [1-2]. Gas gangrene is either an endogenous infection caused by contamination from a clostridial focus in the body (spontaneous, atraumatic) or an exogenous infection found mostly in patients with compound and/or complicated fractures with extensive soft tissue injuries after trauma (non-spontaneous, traumatic). The onset of gas gangrene may occur between one to six hours after injury or operation and begins with severe and sudden pain in the infected area before the clinical signs appear.
View Article and Find Full Text PDFCureus
June 2025
Cardiothoracic Surgery, University of South Florida, Tampa, USA.
Managing anticoagulation in patients with mechanical heart valves who develop a spontaneous intracranial hemorrhage is a challenging clinical scenario. Currently, there are no established guidelines on the optimal timing for the resumption of anticoagulation in this high-risk population. We report a case of a 61-year-old male with mechanical mitral and aortic valves on warfarin therapy for 9 years who presented with atraumatic subdural hematomas.
View Article and Find Full Text PDFRadiol Case Rep
September 2025
General Surgery, High Specialty Medical Unit, Specialty Hospital, National Western Medical Center, Mexican Social Security Institute, Guadalajara, Mexico.
Spontaneous splenic rupture is a rare, life-threatening event, infrequently associated with congenital factor XIII deficiency, a rare coagulation disorder. We present a case of an 18-year-old female with known factor XIII deficiency who presented with acute abdominal pain and was diagnosed with spontaneous splenic rupture. The patient underwent splenectomy due to hemodynamic instability and massive hemorrhage.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Department of General and Emergency Surgery, Ospedale dei Castelli (NOC), ASL Roma 6, Rome, Italy.
Introduction: Atraumatic Splenic Rupture (ASR) is a very rare and potentially life-threatening event associated with Epstein Barr Virus (EBV)-induced mononucleosis; it occurs in <0.5% of overall cases. The aim of the present study was to publish a case report of the ASR and to present a mini review of the international literature.
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