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http://dx.doi.org/10.1007/s12022-024-09823-2 | DOI Listing |
Anal Chim Acta
November 2025
Department of Analytical Chemistry, Faculty of Chemistry, Alzahra University, Vanak, Tehran, Iran; Analytical and Bioanalytical Research Centre, Alzahra University, Vanak, Tehran, Iran. Electronic address:
Background: Determination of the estradiol hormone in urine is crucial for evaluating congenital adrenal hyperplasia, certain hormone-producing ovarian tumors, polycystic ovary syndrome, liver disease, pregnancy, and infertility. On the other hand, steroid hormones can have destructive effects on the environment, animals, and the endocrine system of humans. Consequently, accurately measuring this hormone's concentration in trace amounts is essential for environmental safety and human health.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, PR China. Electronic address:
Background: Breast-conserving surgery (BCS) is the primary surgical approach for patients with breast cancer. The accurate determination of surgical margins during BCS is critical for patient prognosis; however, time constraints and limitations in current pathological techniques often prevent pathologists from performing this assessment intraoperatively. The inability to reliably assess margins during surgery can lead to incomplete tumor removal and the need for additional surgeries.
View Article and Find Full Text PDFRedox Biol
September 2025
National Clinical Research Center for Geriatric Diseases, The Second Medical Center, Chinese PLA General Hospital, 100853, Beijing, China; Institute of Geriatric Medicine, The Second Medical Center, Chinese PLA General Hospital, 100853, Beijing, China.
Small extracellular vesicles (sEVs) critically orchestrate inter-tissue and inter-organ communications and may play essential roles in heart-tumor interaction. However, whether cancer-secreted sEVs affect the progression of doxorubicin-induced cardiotoxicity (DOXIC) via orchestrating the tumor cell-cardiomyocyte crosstalk has not yet been explored. Herein, we reveal that Doxorubicin (DOX)-treated breast cancer cells secrete sEVs (D-BCC-sEVs) that exacerbate DOX-induced ferroptosis of human iPSC-derived cardiomyocytes (hiCMs).
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Laboratory of Tumor Immunology, The first Hospital of Jilin University, Changchun, 130021, China. Electronic address:
The aim was to investigate the pharmacological effects of a polysaccharide isolated from Pleurotus citrinopileatus on ulcerative colitis (UC). One polysaccharide, CP-2-2, was isolated and purified from P. citrinopileatus body fruit using chromatographic methods.
View Article and Find Full Text PDFSTAR Protoc
September 2025
Macrophage Lab, Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Cancer Researc
Interstitial macrophages increase significantly during lung metastasis and may contribute to tumor dissemination. However, isolating them is challenging due to their localization within lung tissue and phenotypic overlap with other immune cells. Here, we present a protocol for isolating and characterizing murine interstitial macrophages.
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