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http://dx.doi.org/10.1038/s43016-024-01030-w | DOI Listing |
J Am Chem Soc
August 2025
School of Advanced Material Science and Engineering, Sungkyunkwan University (SKKU), Suwon, Gyeonggi-do 16419, Republic of Korea.
Downsizing noble metal catalysts is essential for improving atomic efficiency in sustainable energy applications. Typically, strategies focus on anchoring atomically scaled catalysts onto heteroatom-rich substrates, but these interactions can unintentionally alter the electronic structure of the catalyst, complicating the hydrogen evolution reaction (HER) mechanism. This study focuses on elucidating the interfacial mechanism of HER using structurally well-defined platinum single-atom (Pt SA) electrocatalysts.
View Article and Find Full Text PDFCurr Oncol
July 2025
Division of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
(1) Background: Wilms' tumor (WT) is the most common pediatric renal malignancy. Although survival outcomes have improved with multimodal therapy, the optimal sequence of surgery and chemotherapy remains debated, particularly in resource-limited settings. This study evaluates the effect of treatment strategy on surgical complications and survival, utilizing two decades of data from Thai tertiary centers.
View Article and Find Full Text PDFEnviron Sci Technol
August 2025
Electric Vehicle Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
We assess the cradle-to-grave greenhouse gas (GHG) emissions of current (2025) light-duty vehicles (LDV) across powertrains, vehicle classes, and locations. We create driver archetypes (commuters, occasional long-distance travelers, contractors), simulate different use patterns (drive cycles, utility factors, cargo loads) and characterize GHG emissions using an attributional approach. Driven by grid decarbonization and improved electric vehicle efficiency, we are first to report electric vehicles have lower GHG emissions than gasoline vehicles in every county across the contiguous United States.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Radiation Oncology, University of Utah, Salt Lake City, Utah, USA.
Background: Radiotherapy treatment planning is a time-consuming task that requires expert and skilled manpower, particularly for weight adjustment. Valuable attempts have been made to automate the treatment planning process as well as decrease computation time in recent years. Artificial intelligence tools and a knowledge-based planning (KBP) approach have played considerable roles in this regard.
View Article and Find Full Text PDFThyroid
August 2025
Department of Endocrine Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
The use of multikinase inhibitors (MKIs) in thyroid cancer has been established to downsize and facilitate resection of poorly differentiated, differentiated high-grade, anaplastic, and medullary thyroid cancer. Case reports and case series have suggested the potential use of MKIs as neoadjuvant therapies for locally advanced differentiated thyroid cancer (DTC). Our objective was to review available studies and assess if neoadjuvant therapy with MKI can improve surgical and oncological outcomes in patients with locally advanced DTC.
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