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Unlabelled: A 78-year-old man with history of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids syndrome, moderate persistent asthma, pansinusitis, and upper airway cough syndrome presented to the sleep medicine clinic for evaluation of sleep-disordered breathing. Brain magnetic resonance imaging showed lesions in the pons and midbrain. Diagnostic polysomnography was remarkable for central sleep apnea.
Citation: Kokesh KJ, Nguyen M, Presti MF, Syed MA, Wagner MH, Berry RB. A case of central sleep apnea associated with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. . 2020;20(12):1985-1986.
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http://dx.doi.org/10.5664/jcsm.11292 | DOI Listing |
J Virol
September 2025
Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal, India.
High morbidity and mortality associated with human β-coronavirus (CoV) infection highlight the need to determine host responses to infection and develop anti-viral therapies. Gap junction intercellular communication (GJIC), particularly involving Connexin43 (Cx43), is vital for maintaining central nervous system (CNS) homeostasis, and disruption of GJIC is a well-documented pathogenic mechanism among β-coronaviruses. Specifically, murine β-coronavirus, mouse hepatitis virus (MHV-A59) inoculation in the mouse brain causes acute-stage CNS viral spread and chronic neuroinflammatory demyelination while causing pronounced downregulation of Cx43 at the acute stage, reflecting a critical role in CNS pathology.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus N, Denmark.
Background: Taste and smell disorders are more common in individuals with diabetes, particularly among those with low insulin sensitivity or central obesity. These disorders may affect glycaemic control by altering dietary habits. This study aimed to investigate self-reported taste and smell dysfunction in individuals with diabetes and explore associations with clinical and behavioural factors.
View Article and Find Full Text PDFJ Integr Neurosci
August 2025
Neurological Institute of Jiangxi Province and Department of Neurology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, and Xiangya Hospital of Central South University at Jiangxi, 330038 Nanchang, Jiangxi, China.
Sleep paralysis, colloquially known as "ghost pressing" is a state of momentary bodily immobilization occurring either at the onset of sleep or upon awakening. It is characterized by atonia during rapid eye movement (REM) sleep that continues into wakefulness, causing patients to become temporarily unable to talk or move but possessing full consciousness and awareness of their surroundings. Sleep paralysis is listed in the International Classification of Sleep Disorders, 3rd Edition (ICSD-3) as a parasomnia occurring during REM sleep that be classified as either isolated or narcolepsy-associated.
View Article and Find Full Text PDFSleep Adv
July 2025
Lindner Center of HOPE Research Institute, Mason, OH, United States.
Study Objectives: Dim light melatonin onset (DLMO) is the best-established marker of central circadian phase and may contribute to unraveling the role of the circadian system in obesity. This study evaluated DLMO among individuals with obesity using a home-based assessment and explored its clinical correlates and procedural variations.
Method: Fifty-eight women (mean [SD] age 40.
Front Psychiatry
August 2025
School of Public Health, Southeast University, Nanjing, China.
Background: Gender differences in COVID-19-related fear among mental health professionals (MHPs) have been inadequately studied. This study compared the gender differences in prevalence, correlates and network structure of COVID-19 fear among MHPs in China in the post-pandemic era.
Methods: A nationwide cross-sectional study was conducted between January 22 and February 10, 2023.